{"doi":"10.31234/osf.io/kcgp5","title":"Musical rhythm abilities and risk for developmental speech-language problems and disorders: epidemiological and polygenic associations","abstract":"Impaired musical rhythm abilities and developmental speech-language related disorders are biologically and clinically intertwined. Prior work examining their relationship has primarily used small samples; here, we studied associations at population-scale by conducting the largest systematic epidemiological investigation to date (total N = 39,092). Based on existing theoretical frameworks, we predicted that rhythm impairment would be a significant risk factor for speech-language disorders in the general adult population. Findings were consistent across multiple independent datasets and rhythm subskills (including beat synchronization and rhythm discrimination), and aggregate meta-analyzed data showed that rhythm impairment is a modest but consistent risk factor for developmental speech, language, and reading disorders (OR = 1.32 [1.14 – 1.49]; p < .0001). Further, cross-trait polygenic score analyses indicate shared genetic architecture between musical rhythm and reading abilities, providing evidence for genetic pleiotropy between rhythm and language-related phenotypes.","journal":"Goldsmiths (University of London)","year":2024,"id":486737,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9478,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":244444,"name":"Enikő Ladányi","orcid":"0000-0003-2853-682X","position":1,"is_corresponding":false},{"id":294848,"name":"Else Eising","orcid":"0000-0001-9819-1260","position":2,"is_corresponding":false},{"id":1163419,"name":"Yasmina Mekki","orcid":"0000-0002-5733-9721","position":3,"is_corresponding":false},{"id":449632,"name":"Rachana Nitin","orcid":"0000-0002-3331-1580","position":4,"is_corresponding":false},{"id":1040141,"name":"Catherine T. Bush","orcid":"0000-0003-0821-3388","position":5,"is_corresponding":false},{"id":486269,"name":"Daniel E. Gustavson","orcid":"0000-0002-1470-4928","position":6,"is_corresponding":false},{"id":954144,"name":"Manuel Anglada-Tort","orcid":"0000-0003-3421-9361","position":7,"is_corresponding":false},{"id":817857,"name":"Hope Sparks Lancaster","orcid":"0000-0001-9924-9508","position":8,"is_corresponding":false},{"id":89936,"name":"Miriam A Mosing","orcid":"0000-0003-2049-125X","position":9,"is_corresponding":false},{"id":89935,"name":"Fredrik Ullén","orcid":null,"position":10,"is_corresponding":false},{"id":691295,"name":"Cyrille Magne","orcid":"0000-0003-4943-9244","position":11,"is_corresponding":false},{"id":109368,"name":"Simon E. Fisher","orcid":"0000-0002-3132-1996","position":12,"is_corresponding":false},{"id":256114,"name":"Nori Jacoby","orcid":"0000-0003-2868-0100","position":13,"is_corresponding":false},{"id":244448,"name":"Reyna L. Gordon","orcid":"0000-0003-1643-6979","position":14,"is_corresponding":false},{"id":812152,"name":"Srishti Nayak","orcid":"0000-0001-6581-3510","position":0,"is_corresponding":true}],"reference_count":87,"raw_metadata":null,"created_at":"2026-07-19T02:08:01.404471Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}