{"doi":"10.3109/00016348809029862","title":"Clinicopathologic considerations of fusobacteria chorioamnionitis","abstract":"<jats:p>When sought by light microscopy in formalin‐fixed tissue, fusobacteria are apparent in 7–18% of chorioamnionitis cases. Brown and Hopps bacterial staining characteristically visualizes their long, slender and filamentous forms. Fusobacteria‐like organisms in placentae have previously been associated with prematurity. Our findings indicate that perinatal infection with fusobacteria may cause neonatal death from prematurity, rather than from sepsis. In a study of 586 placentae, 14 specimens with chorioamnionitis and fusobacteria‐like organisms were found. On the five occasions when microbiologic tests were made, fusobacteria were isolated. Prematurity of the newborns was associated with twelve of those placentae. Immunofluorescent labelling of the organisms is a helpful but incomplete means of diagnosis. Because fusobacteria antibodies are highly specific, they do not cross‐react with other members of the genus <jats:italic>Fusobacterium.</jats:italic> A typical case is reported, in detail.</jats:p>","journal":"Acta Obstetricia et Gynecologica Scandinavica","year":1988,"id":604192,"datarank":0.5570358100056463,"base_score":3.713572066704308,"endowment":3.713572066704308,"self_citation_contribution":0.5570358100056463,"citation_network_contribution":0.0,"self_endowment_contribution":0.5570358100056463,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":40,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1550111,"name":"Scott Hyde","orcid":null,"position":1,"is_corresponding":false},{"id":1550110,"name":"Geoffrey Altshuler","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Clinicopathologic considerations of fusobacteria chorioamnionitis","abstract":"<jats:p>When sought by light microscopy in formalin‐fixed tissue, fusobacteria are apparent in 7–18% of chorioamnionitis cases. Brown and Hopps bacterial staining characteristically visualizes their long, slender and filamentous forms. Fusobacteria‐like organisms in placentae have previously been associated with prematurity. Our findings indicate that perinatal infection with fusobacteria may cause neonatal death from prematurity, rather than from sepsis. In a study of 586 placentae, 14 specimens with chorioamnionitis and fusobacteria‐like organisms were found. On the five occasions when microbiologic tests were made, fusobacteria were isolated. Prematurity of the newborns was associated with twelve of those placentae. Immunofluorescent labelling of the organisms is a helpful but incomplete means of diagnosis. Because fusobacteria antibodies are highly specific, they do not cross‐react with other members of the genus <jats:italic>Fusobacterium.</jats:italic> A typical case is reported, in detail.</jats:p>","is_dataset_classified":null,"base_score":3.713572066704308,"endowment":3.713572066704308,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"3071072","pmcid":null,"openalex_id":"https://openalex.org/W1966101897","authors":[],"funders":[],"total_grants":0,"fwci":0.9462,"citation_percentile":0.74306789,"influential_citations":0,"citation_trend":[{"year":2012,"count":2},{"year":2015,"count":2},{"year":2016,"count":1},{"year":2017,"count":1},{"year":2018,"count":3},{"year":2019,"count":1},{"year":2020,"count":1},{"year":2021,"count":2},{"year":2022,"count":2},{"year":2023,"count":1}],"oa_status":"closed","license":"http://onlinelibrary.wiley.com/termsAndConditions#vor","oa_locations":[{"url":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.3109%2F00016348809029862","host_type":"publisher"},{"url":"https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.3109/00016348809029862","host_type":"publisher"},{"url":"https://doi.org/10.3109/00016348809029862","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/3071072","host_type":"repository"}],"fields_of_study":["Preterm Birth and Chorioamnionitis","Congenital Diaphragmatic Hernia Studies","Neonatal Respiratory Health Research","Adult","Chorioamnionitis","Female","Fluorescent Antibody Technique","Fusobacterium Infections","Humans","Infant, Newborn","Male","Obstetric Labor, Premature","Placenta","Pregnancy"],"mesh_terms":["Adult","Chorioamnionitis","Female","Fluorescent Antibody Technique","Fusobacterium Infections","Humans","Infant, Newborn","Obstetric Labor, Premature","Male","Placenta","Pregnancy"],"keywords":["Fusobacteria","Chorioamnionitis","Medicine","Fusobacterium","Immunology","Microbiology","Pathology","Fetus","Biology","Pregnancy","Bacteroides","Bacteria","Bacteroidetes"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-29T23:31:46.006315Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}