{"doi":"10.29252/scil.2020.jlsb3","title":"Alignment of SARS-CoV-2 in comparison with other coronaviruses","abstract":null,"journal":"Journal of Life Science and Biomedicine","year":2020,"id":595237,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1524129,"name":"Mohamed Samy ABOUSENNA","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Alignment of SARS-CoV-2 in comparison with other coronaviruses","abstract":"Introduction  Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is currently declared as pandemic according to WHO  It was initially detected in China and then rapidly transmitted to most world territories  The SARS-CoV-2 has an ambiguous origin, with unique properties, pathogenesis and transmission rate, thus making its prevention and control a difficult task  Aim  In the present study, we investigated the origin hypotheses through conducting multiple alignments and phylogenetic analysis for surface glycoprotein and complete genome of SARS-CoV-2 in comparison with other coronaviruses of different species  All the data used in this study were obtained from NCBI online database and analyzed using Blast tool  The alignment and phylogenetic analysis of SARS-CoV-2 surface glycoprotein in comparison with spike glycoprotein of Bat coronavirus RaTG13, Pangolin coronavirus, Bat SARS-like coronavirus, SARS-CoV, BCoV, IBV, ECoV, MHV-JHM, MERS-CoV, CCoV, HCoV-229E and FCOV indicated close identical matching to spike protein for Bat coronavirus RaTG13 and Pangolin coronavirus isolate MP789  The similarity was 97 41% and 96 67%, respectively  Also, multiple alignments of complete genome for SARS-CoV-2 and Bat coronavirus RaTG13 showed a significant similarity of 96 11%  Recommendation  Therefore, these relevant results strongly recommend the origin hypothesis of SARS-CoV-2 from Bat coronavirus RaTG13  The nature of evolution is considered to be natural selection  © 2020","is_dataset_classified":null,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21097893","pmcid":null,"openalex_id":"https://openalex.org/W3024980608","authors":[],"funders":[],"total_grants":0,"fwci":0.0254,"citation_percentile":0.37807108,"influential_citations":0,"citation_trend":[{"year":2022,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"http://www.jlsb.science-line.com/attachments/article/77/JLSB%2010(2)%2017-20,%202019-Alignment%20of%20SARS-CoV-2%20(COVID-19).pdf","host_type":"publisher"},{"url":"https://doi.org/10.29252/scil.2020.jlsb3","host_type":"journal"}],"fields_of_study":["SARS-CoV-2 and COVID-19 Research","vaccines and immunoinformatics approaches","Animal Virus Infections Studies"],"mesh_terms":[],"keywords":["Coronavirus","Pangolin","Phylogenetic tree","Virology","Biology","Pandemic","Genome","Betacoronavirus","Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","Transmission (telecommunications)","Coronavirus disease 2019 (COVID-19)","Phylogenetics","Lineage (genetic)","Genetics","Evolutionary biology","Gene","Medicine","Disease","Computer science","Infectious disease (medical specialty)"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-27T16:56:27.165855Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}