{"doi":"10.29026/oes.2025.240027","title":"Tip-enhanced Raman scattering of glucose molecules","abstract":null,"journal":"Opto-Electronic Science","year":2025,"id":637826,"datarank":0.48283137373023016,"base_score":3.2188758248682006,"endowment":3.2188758248682006,"self_citation_contribution":0.48283137373023016,"citation_network_contribution":0.0,"self_endowment_contribution":0.48283137373023016,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":24,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1656326,"name":"Chao Meng","orcid":null,"position":1,"is_corresponding":false},{"id":1656327,"name":"Donghua Yue","orcid":null,"position":2,"is_corresponding":false},{"id":1180533,"name":"Lei Xu","orcid":"0000-0001-8280-3162","position":3,"is_corresponding":false},{"id":1592114,"name":"Ting Mei","orcid":null,"position":4,"is_corresponding":false},{"id":1656328,"name":"Wending Zhang","orcid":null,"position":5,"is_corresponding":false},{"id":586411,"name":"Zhonglin Xie","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Tip-enhanced Raman scattering of glucose molecules","abstract":"Glucose molecules are of great significance being one of the most important molecules in metabolic chain. However, due to the small Raman scattering cross-section and weak/non-adsorption on bare metals, accurately obtaining their \"fingerprint information\" remains a huge obstacle. Herein, we developed a tip-enhanced Raman scattering (TERS) technique to address this challenge. Adopting an optical fiber radial vector mode internally illuminates the plasmonic fiber tip to effectively suppress the background noise while generating a strong electric-field enhanced tip hotspot. Furthermore, the tip hotspot approaching the glucose molecules was manipulated via the shear-force feedback to provide more freedom for selecting substrates. Consequently, our TERS technique achieves the visualization of all Raman modes of glucose molecules within spectral window of 400–<styled-content style-type=\"number\">3200</styled-content> cm<sup>−1</sup>, which is not achievable through the far-field/surface-enhanced Raman, or the existing TERS techniques. Our TERS technique offers a powerful tool for accurately identifying Raman scattering of molecules, paving the way for biomolecular analysis.","is_dataset_classified":null,"base_score":3.2188758248682006,"endowment":3.2188758248682006,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19767382","pmcid":null,"openalex_id":"https://openalex.org/W4407935442","authors":[],"funders":[],"total_grants":0,"fwci":18.2626,"citation_percentile":0.99436937,"influential_citations":0,"citation_trend":[{"year":2025,"count":8},{"year":2026,"count":16}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://www.oejournal.org/oes/en/article/pdf/preview/10.29026/oes.2025.240027.pdf","host_type":"journal"},{"url":"https://www.oejournal.org/oes/en/article/pdf/preview/10.29026/oes.2025.240027.pdf","host_type":"publisher"},{"url":"https://doi.org/10.29026/oes.2025.240027","host_type":"journal"},{"url":"https://doaj.org/article/1aa9def380264eb0a7ec6d3ee254f579","host_type":"repository"}],"fields_of_study":["Spectroscopy Techniques in Biomedical and Chemical Research","Gold and Silver Nanoparticles Synthesis and Applications","Spectroscopy and Quantum Chemical Studies"],"mesh_terms":[],"keywords":["Raman scattering","Raman spectroscopy","Molecule","X-ray Raman scattering","Materials science","Scattering","Chemistry","Optics","Physics","Organic chemistry"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Zero hunger"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T19:35:54.240882Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}