{"doi":"10.26226/morressier.5d4980ca8fb7e44098e72b36","title":"Senescence surveillance maintains genomic and functional differentiation in pre-malignant tumors","abstract":null,"journal":null,"year":null,"id":641750,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1668747,"name":"Ellen Brenner","orcid":null,"position":1,"is_corresponding":false},{"id":1668748,"name":"Nadine Simon","orcid":null,"position":2,"is_corresponding":false},{"id":1668749,"name":"Martin Roecken","orcid":null,"position":3,"is_corresponding":false},{"id":197040,"name":"Thomas Wieder","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Senescence surveillance maintains genomic and functional differentiation in pre-malignant tumors","abstract":"Different animal models as well as histological studies using samples from cancer patients clearly showed that cellular senescence is a barrier against tumor progression. Yet, recent data question this concept suggesting that senescent cells may also promote tumor progression. By adopting a senescence-associated secretory phenotype, senescence signaling may even induce","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19767382","pmcid":null,"openalex_id":"https://openalex.org/W4211095890","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"gold","license":"cc-by-nc","oa_locations":[{"url":"https://doi.org/10.26226/morressier.5d4980ca8fb7e44098e72b36","host_type":""},{"url":"https://doi.org/10.26226/morressier.5d4980ca8fb7e44098e72b36","host_type":""},{"url":"https://openresearchlibrary.org/viewer/478fdaaf-18c6-4cbd-83b9-6ccb7a82d57e","host_type":"repository"}],"fields_of_study":["Telomeres, Telomerase, and Senescence","Epigenetics and DNA Methylation","Immune cells in cancer"],"mesh_terms":[],"keywords":["Senescence","Phenotype","Biology","Cellular senescence","Cancer research","Tumor progression","Cancer","Cell biology","Gene","Genetics"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-07T20:07:22.043028Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}