{"doi":"10.2500/aap.2021.42.200109","title":"Efficacy of sublingual immunotherapy tablets in dust mite and pollen allergy","abstract":"<jats:p>The latest evidence on the mechanisms, efficacy, and safety of sublingual immunotherapy (SLIT) was reviewed. Interleukin (IL) 35 and IL-35‐producing regulatory T cells were assessed as new biomarkers for SLIT responsiveness. A detailed analysis of clinical studies, including\n timothy grass pollen, 5-grass pollen, ragweed, and house-dust mite SLIT tablets, was provided, including a comparative analysis of efficacy and safety of SLIT versus subcutaneous immunotherapy.</jats:p>","journal":"Allergy and Asthma Proceedings","year":2021,"id":25979,"datarank":0.3356641814437974,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.09424849457868234,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.09424849457868234,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":4,"citers_with_citation_signal":2,"citers_with_endowment":2,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":151472,"name":"Ilona DuBuske","orcid":null,"position":1,"is_corresponding":false},{"id":151473,"name":"Lawrence M. DuBuske","orcid":null,"position":2,"is_corresponding":false},{"id":151471,"name":"Yuriy Bisyuk","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"33404387","pmcid":null,"openalex_id":"https://openalex.org/W3120124529","authors":[],"funders":[],"total_grants":0,"fwci":0.2613,"citation_percentile":0.50834092,"influential_citations":1,"citation_trend":[{"year":2021,"count":1},{"year":2024,"count":1},{"year":2025,"count":1},{"year":2026,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://www.ingentaconnect.com/content/ocean/aap/2021/00000042/00000001/art00012","host_type":"publisher"},{"url":"https://doi.org/10.2500/aap.2021.42.200109","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/33404387","host_type":"repository"}],"fields_of_study":["Allergic Rhinitis and Sensitization","Dermatology and Skin Diseases","Vector-borne infectious diseases","Medicine","Administration, Sublingual","Allergens","Animals","Antigens, Dermatophagoides","Biomarkers, Pharmacological","Desensitization, Immunologic","Humans","Hypersensitivity","Injections, Subcutaneous","Pollen","Pyroglyphidae","Treatment Outcome"],"mesh_terms":["Administration, Sublingual","Allergens","Animals","Desensitization, Immunologic","Humans","Hypersensitivity","Injections, Subcutaneous","Pollen","Treatment Outcome","Antigens, Dermatophagoides","Pyroglyphidae","Biomarkers, Pharmacological"],"keywords":["Sublingual immunotherapy","Slit","Ragweed","Medicine","Pollen","Allergy","House dust mite","Dust mites","Immunotherapy","Mite","Immunology","Dermatology","Allergen","Immune system","Botany"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-08T10:07:54.001493Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}