{"doi":"10.24124/2017/1386","title":"Investigating splicing in two disparate organisms: a highly reduced spliceosome in Cyandioschyzon Merolae and additional functionality in Saccharomyces Cerevisiae's PRP24","abstract":null,"journal":null,"year":null,"id":599218,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1535740,"name":"Anthony Daniele","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Investigating splicing in two disparate organisms: a highly reduced spliceosome in Cyandioschyzon Merolae and additional functionality in Saccharomyces Cerevisiae's PRP24","abstract":"Splicing, the removal of non-protein coding introns from pre-mRNA, is a critical step in eukaryotic gene expression that is facilitated by a large, dynamic ribonucleoprotein complex known as the spliceosome. The spliceosome is composed of five subcomponents of small nuclear ribonucleoprotein particles consisting of a snRNA and their associated proteins; these \"snRNPs\" are referred to as U1, U2, U4, U5, and U6. Recently, the red alga Cyanidioschyzon merolae was found to be lacking the U1 snRNA, raising questions of whether U1 proteins are also absent and to what extent the rest of the spliceosome is reduced.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"21097893","pmcid":null,"openalex_id":"https://openalex.org/W4253748252","authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"gold","license":null,"oa_locations":[{"url":"https://unbc.arcabc.ca/islandora/object/unbc%3A17372/datastream/PDF/view","host_type":""},{"url":"https://unbc.arcabc.ca/islandora/object/unbc%3A17372/datastream/PDF/view","host_type":""},{"url":"https://doi.org/10.24124/2017/1386","host_type":""},{"url":"https://arcabc.ca/islandora/object/unbc%3A17372","host_type":"repository"}],"fields_of_study":["RNA Research and Splicing","RNA and protein synthesis mechanisms","RNA modifications and cancer"],"mesh_terms":[],"keywords":["Spliceosome","snRNP","RNA splicing","Minor spliceosome","Prp24","Small nuclear RNA","Small nuclear ribonucleoprotein","Ribonucleoprotein","Intron","Biology","SR protein","Genetics","Splicing factor","Cell biology","Exonic splicing enhancer","Saccharomyces cerevisiae","RNA-binding protein","Gene","RNA","Computational biology","Non-coding RNA"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Zero hunger"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-28T19:54:36.648788Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}