{"doi":"10.2337/dc24-1956","title":"Carbohydrates-Last Food Order Improves Time in Range and Reduces Glycemic Variability","abstract":"Advancements in continuous glucose monitoring technology allow nuanced assessment of glycemic control.Glycemic variability (GV) and time spent with glucose in target range time-in-range (TIR) are now recognized risk predictors for diabetes-related complications and are associated with cardiovascular risk, even for patients with well-controlled HbA 1c (1,2).Prior research by our group and others demonstrates that besides carbohydrate amount and type, the timing of carbohydrate consumption during a meal significantly impacts regulation of postprandial glucose levels (3-5).In acute crossover studies, consuming fibrous vegetables and protein 10 min before carbohydrate (i.e., carbohydrates-last [CL] food order) reduced incremental postprandial glucose peaks and glycemic variability for up to 3 h in comparison with the reverse sequence (carbohydrates-first [CF] food order) in patients with type 2 diabetes (T2D) (4).Here, in this study (clinical trial reg.no.NCT04738799, clinicaltrials.gov)we examine the glycemic effects of nutrient sequencing without a rest interval between consumption of meal components-under","journal":"Diabetes Care","year":2024,"id":456931,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9588,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1282286,"name":"Kathyayini Palepu","orcid":null,"position":1,"is_corresponding":false},{"id":1132253,"name":"Ampadi Karan","orcid":null,"position":2,"is_corresponding":false},{"id":441184,"name":"Katie C. Hootman","orcid":"0000-0003-0476-3454","position":3,"is_corresponding":false},{"id":1281773,"name":"Jessica Riad","orcid":"0009-0000-6011-4104","position":4,"is_corresponding":false},{"id":1282287,"name":"Sriharsha Sripadrao","orcid":null,"position":5,"is_corresponding":false},{"id":747297,"name":"Alice Zhao","orcid":"0000-0001-5845-8071","position":6,"is_corresponding":false},{"id":1132257,"name":"Ashley Giannita","orcid":null,"position":7,"is_corresponding":false},{"id":318726,"name":"Debra D’Angelo","orcid":"0000-0001-6212-5640","position":8,"is_corresponding":false},{"id":623450,"name":"Laura Alonso","orcid":"0000-0001-5056-8970","position":9,"is_corresponding":false},{"id":107052,"name":"Louis J. Aronne","orcid":"0000-0002-9890-9401","position":10,"is_corresponding":false},{"id":623449,"name":"Alpana P. Shukla","orcid":"0000-0002-4763-2350","position":11,"is_corresponding":false},{"id":1282285,"name":"Samir Touhamy","orcid":null,"position":0,"is_corresponding":true}],"reference_count":6,"raw_metadata":null,"created_at":"2026-07-19T02:03:32.516678Z","pmid":"39688621","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}