{"doi":"10.2337/dc20-2085","title":"Remote Continuous Glucose Monitoring With a Computerized Insulin Infusion Protocol for Critically Ill Patients in a COVID-19 Medical ICU: Proof of Concept","abstract":"OBJECTIVE: The use of remote real-time continuous glucose monitoring (CGM) in the hospital has rapidly emerged to preserve personal protective equipment and reduce potential exposures during coronavirus disease 2019 (COVID-19). RESEARCH DESIGN AND METHODS: We linked a hybrid CGM and point-of-care (POC) glucose testing protocol to a computerized decision support system for continuous insulin infusion and integrated a validation system for sensor glucose values into the electronic health record. We report our proof-of-concept experience in a COVID-19 intensive care unit. RESULTS: All nine patients required mechanical ventilation and corticosteroids. During the protocol, 75.7% of sensor values were within 20% of the reference POC glucose with an associated average reduction in POC of 63%. Mean time in range (70-180 mg/dL) was 71.4 ± 13.9%. Sensor accuracy was impacted by mechanical interferences in four patients. CONCLUSIONS: A hybrid protocol integrating real-time CGM and POC is helpful for managing critically ill patients with COVID-19 requiring insulin infusion.","journal":"Diabetes Care","year":2021,"id":150650,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":90,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9576,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":640497,"name":"Eileen R. Faulds","orcid":"0000-0003-2315-1146","position":1,"is_corresponding":false},{"id":640498,"name":"Tara L. Walker","orcid":"0000-0002-8472-0245","position":2,"is_corresponding":false},{"id":641369,"name":"Debbie Vigliotti","orcid":null,"position":3,"is_corresponding":false},{"id":641370,"name":"Marina Rabinovich","orcid":null,"position":4,"is_corresponding":false},{"id":641371,"name":"Joi Hester","orcid":null,"position":5,"is_corresponding":false},{"id":542342,"name":"Limin Peng","orcid":"0000-0002-8042-3112","position":6,"is_corresponding":false},{"id":640499,"name":"Barbara McLean","orcid":"0009-0003-7379-3443","position":7,"is_corresponding":false},{"id":641372,"name":"Patricia Hannon","orcid":null,"position":8,"is_corresponding":false},{"id":641373,"name":"Norma Poindexter","orcid":null,"position":9,"is_corresponding":false},{"id":641374,"name":"Petrena Saunders","orcid":null,"position":10,"is_corresponding":false},{"id":263837,"name":"M. Citlalli Perez‐Guzman","orcid":"0000-0003-3406-7193","position":11,"is_corresponding":false},{"id":640500,"name":"Seema S. Tekwani","orcid":"0000-0002-7395-1160","position":12,"is_corresponding":false},{"id":24174,"name":"Greg S. Martin","orcid":"0000-0002-9684-7593","position":13,"is_corresponding":false},{"id":228523,"name":"Guillermo E. Umpierrez","orcid":"0000-0002-3252-5026","position":14,"is_corresponding":false},{"id":246565,"name":"Shivani Agarwal","orcid":"0000-0003-4506-3702","position":15,"is_corresponding":false},{"id":612786,"name":"Kathleen Dungan","orcid":"0000-0003-1289-1595","position":16,"is_corresponding":false},{"id":263838,"name":"Francisco J. Pasquel","orcid":"0000-0002-3845-6703","position":17,"is_corresponding":false},{"id":263836,"name":"Georgia M. Davis","orcid":"0000-0001-9671-0063","position":0,"is_corresponding":true}],"reference_count":17,"raw_metadata":null,"created_at":"2026-07-18T23:43:06.501849Z","pmid":"33563655","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}