{"doi":"10.2307/3280054","title":"Characterization and Isolation of Concanavalin a Binding Sites from the Epidermis of S. mansoni","abstract":null,"journal":"The Journal of Parasitology","year":1977,"id":643349,"datarank":0.6166310796259968,"base_score":4.110873864173311,"endowment":4.110873864173311,"self_citation_contribution":0.6166310796259968,"citation_network_contribution":0.0,"self_endowment_contribution":0.6166310796259968,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":60,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1673869,"name":"John L. Seed","orcid":null,"position":1,"is_corresponding":false},{"id":1673868,"name":"James L. Bennett","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Characterization and Isolation of Concanavalin a Binding Sites from the Epidermis of S. mansoni","abstract":"Using concanavalin A labeled with tritium and fluorescein isothiocyanate we studied the binding properties of this plant lectin to adult paired schistosomes. Using concanavalin A coupled to a sepharose column we attempted to isolate and characterize concanavalin A binding molecules from the epidermis of adult schistosomes. Our results indicate the presence of specific concanavalin A binding sites on the surface of adult Schistosoma mansoni. A significant percentage of the concanavalin A was specifically bound and showed characteristics similar to that identical in other concanavalin A binding tissues. The parasite's concanavalin A binding sites appear to be 2 or 3 high molecular weight glycoproteins. There is some indication that glycoproteins associated with the worm's epidermis function as enzyme(s). The immunological significance of these glycoproteins has not been determined.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"870665","pmcid":null,"openalex_id":null,"authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"closed","license":null,"oa_locations":[],"fields_of_study":[],"mesh_terms":["Skin","Animals","Mice","Schistosoma mansoni","Calcium Chloride","Glycoproteins","Methylmannosides","Saponins","Concanavalin A","Receptors, Concanavalin A","Receptors, Drug","Molecular Weight","Male"],"keywords":[],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-08T15:55:11.883991Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}