{"doi":"10.22452/jummec.vol12no2.3","title":"VENTRICULAR DYSSYNCHRONY IS COMMON AMONG HEART FAILURE PATIENTS WITH NARROW QRS COMPLEX","abstract":null,"journal":"Journal of Health and Translational Medicine","year":2009,"id":637836,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1656354,"name":"Yaakob ZH","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"VENTRICULAR DYSSYNCHRONY IS COMMON AMONG HEART FAILURE PATIENTS WITH NARROW QRS COMPLEX","abstract":"Current selection guideline for CRT uses broad QRS duration (>120 ms) as a marker for ventricular dyssynchrony. However, more recent data supports mechanical marker specifically measured by Tissue Doppler Imaging (TDI) as a better criterion to predict response to CRT. Sixty seven patients with significant left ventricular dysfunction (EF less than 40%) and narrow QRS complex were prospectively enrolled. They underwent Tissue Doppler Imaging (TDI) study to evaluateintraventricular mechanical dyssynchrony. Dyssynchrony index which is defined as standard deviation of time to peak systolic velocity in twelve ventricular segments was measured. A value greater than 32.6 is taken to reflect significant ventricular dyssynchrony. Overall 38 patients (56.7%) demonstrated significant dyssynchrony. There was no significant correlation between QRS duration and the Ts-SD-12 (r = 0.14, p = 0.11). Ventricular mechanical dyssynchrony is commonin patients with normal QRS duration. Therefore, QRS duration alone will miss a substantial proportion of suitable patients for CRT and therefore deny them this adjunct therapy. We propose echocardiographic parameters, specifically TDI, to be included in patient selection criteria for CRT.","is_dataset_classified":null,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19767382","pmcid":null,"openalex_id":"https://openalex.org/W1952508477","authors":[],"funders":[],"total_grants":0,"fwci":0.1916,"citation_percentile":0.58723854,"influential_citations":0,"citation_trend":[{"year":2016,"count":1}],"oa_status":"gold","license":null,"oa_locations":[{"url":"https://jummec.um.edu.my/index.php/jummec/article/download/4621/2414","host_type":"journal"},{"url":"https://jummec.um.edu.my/index.php/jummec/article/download/4621/2414","host_type":"publisher"},{"url":"https://doi.org/10.22452/jummec.vol12no2.3","host_type":"journal"}],"fields_of_study":["Cardiac pacing and defibrillation studies","Cardiac Arrhythmias and Treatments","Cardiomyopathy and Myosin Studies"],"mesh_terms":[],"keywords":["QRS complex","Medicine","Cardiology","Internal medicine","Ventricular dyssynchrony","Doppler imaging","Heart failure","Guideline","Cardiac resynchronization therapy","Diastole","Blood pressure","Ejection fraction","Pathology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-06T19:37:19.248972Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}