{"doi":"10.2217/fmb-2016-0104","title":"Potential of a Lytic Bacteriophage to Disrupt\n            <i>Acinetobacter Baumannii</i>\n            Biofilms\n            <i>in Vitro</i>","abstract":null,"journal":"Future Microbiology","year":2016,"id":642568,"datarank":1.67853391713067,"base_score":3.713572066704308,"endowment":3.713572066704308,"self_citation_contribution":0.5570358100056463,"citation_network_contribution":1.1214981071250236,"self_endowment_contribution":0.5570358100056463,"citer_contribution":1.1214981071250236,"corpus_percentile":null,"corpus_rank":null,"citation_count":40,"citer_count":35,"citers_with_citation_signal":31,"citers_with_endowment":31,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1671491,"name":"Zhiqiang Mi","orcid":null,"position":1,"is_corresponding":false},{"id":1671492,"name":"Wenkai Niu","orcid":null,"position":2,"is_corresponding":false},{"id":1671493,"name":"Xiaoping An","orcid":null,"position":3,"is_corresponding":false},{"id":532151,"name":"Xin Yuan","orcid":"0000-0002-8311-7524","position":4,"is_corresponding":false},{"id":1671494,"name":"Huiying Liu","orcid":null,"position":5,"is_corresponding":false},{"id":755728,"name":"Yong Wang","orcid":"0000-0002-8349-7555","position":6,"is_corresponding":false},{"id":1671495,"name":"Yuzhong Feng","orcid":null,"position":7,"is_corresponding":false},{"id":15931,"name":"Yong Huang","orcid":"0000-0001-5953-6908","position":8,"is_corresponding":false},{"id":77846,"name":"Xianglilan Zhang","orcid":"0000-0002-4946-4880","position":9,"is_corresponding":false},{"id":643624,"name":"Zhiyi Zhang","orcid":null,"position":10,"is_corresponding":false},{"id":70982,"name":"Hang Fan","orcid":"0000-0002-4127-7140","position":11,"is_corresponding":false},{"id":1061082,"name":"Fan Peng","orcid":null,"position":12,"is_corresponding":false},{"id":1671496,"name":"Puyuan Li","orcid":null,"position":13,"is_corresponding":false},{"id":104801,"name":"Yigang Tong","orcid":"0000-0002-8503-8045","position":14,"is_corresponding":false},{"id":18594,"name":"Changqing Bai","orcid":null,"position":15,"is_corresponding":false},{"id":374729,"name":"Yannan Liu","orcid":"0000-0001-5781-2729","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Potential of a Lytic Bacteriophage to Disrupt\n            <i>Acinetobacter Baumannii</i>\n            Biofilms\n            <i>in Vitro</i>","abstract":"AIM: The ability of Acinetobacter baumannii to form biofilms and develop antibiotic resistance makes it difficult to control infections caused by this bacterium. In this study, we explored the potential of a lytic bacteriophage to disrupt A. baumannii biofilms. MATERIALS & METHODS: The potential of the lytic bacteriophage to disrupt A. baumannii biofilms was assessed by performing electron microscopy, live/dead bacterial staining, crystal violet staining and by determining adenosine triphosphate release. RESULTS: The bacteriophage inhibited the formation of and disrupted preformed A. baumannii biofilms. Results of disinfection assay showed that the lytic bacteriophage lysed A. baumannii cells suspended in blood or grown on metal surfaces. CONCLUSION: These results suggest the potential of the lytic bacteriophage to disrupt A. baumannii biofilms.","is_dataset_classified":null,"base_score":3.713572066704308,"endowment":3.713572066704308,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"27538011","pmcid":null,"openalex_id":"https://openalex.org/W2518588714","authors":[],"funders":[{"funder_name":"Beijing Natural Science Foundation","grant_id":"7142118","title":null},{"funder_name":"National Natural Science Foundation of China","grant_id":"81572045","title":null},{"funder_name":"National Hi-Tech Research and Development (863) Program of China","grant_id":"2014AA021–402, 2015AA020–108","title":null},{"funder_name":"Capital Characteristic Clinic Project of Beijing","grant_id":"Z121107001012127","title":null}],"total_grants":4,"fwci":2.2237,"citation_percentile":0.87117135,"influential_citations":0,"citation_trend":[{"year":2017,"count":1},{"year":2018,"count":2},{"year":2019,"count":5},{"year":2020,"count":5},{"year":2021,"count":5},{"year":2022,"count":7},{"year":2023,"count":3},{"year":2024,"count":4},{"year":2025,"count":6},{"year":2026,"count":2}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://www.tandfonline.com/doi/pdf/10.2217/fmb-2016-0104","host_type":"publisher"},{"url":"https://doi.org/10.2217/fmb-2016-0104","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/27538011","host_type":"repository"}],"fields_of_study":["Bacteriophages and microbial interactions","Vibrio bacteria research studies","Bacillus and Francisella bacterial research","Acinetobacter Infections","Acinetobacter baumannii","Adenosine Triphosphate","Anti-Bacterial Agents","Bacteriophages","Biofilms","China","Disinfection","Drug Resistance, Multiple, Bacterial","Humans","Phage Therapy","Sputum","Staining and Labeling"],"mesh_terms":["Phage Therapy","Acinetobacter Infections","Adenosine Triphosphate","Anti-Bacterial Agents","Bacteriophages","China","Disinfection","Humans","Sputum","Staining and Labeling","Biofilms","Drug Resistance, Multiple, Bacterial","Acinetobacter baumannii"],"keywords":["Lytic cycle","Acinetobacter baumannii","Bacteriophage","Biofilm","Microbiology","Lysis","Biology","Bacteria","Crystal violet","Virology","Chemistry","Molecular biology","Virus","Escherichia coli","Biochemistry","Pseudomonas aeruginosa","Genetics","Resistance","Disinfection"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-08T00:18:19.755881Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}