{"doi":"10.2196/24893","title":"Access to Technology and Preferences for an mHealth Intervention to Promote Medication Adherence in Pediatric Acute Lymphoblastic Leukemia: Approach Leveraging Behavior Change Techniques","abstract":"BACKGROUND: Suboptimal adherence to 6-mercaptopurine (6-MP) is prevalent in pediatric acute lymphoblastic leukemia (ALL) and associated with increased risk of relapse. Rapid uptake of personal technology makes mobile health (mHealth) an attractive platform to promote adherence. OBJECTIVE: Study objectives were to examine access to mobile technology and preferences for an mHealth intervention to improve medication adherence in pediatric ALL. METHODS: A cross-sectional survey was administered in oncology clinic to parents of children with ALL as well as adolescents and young adults (AYAs) with ALL receiving maintenance chemotherapy. RESULTS: A total of 49 parents (median age [IQR] 39 [33-42] years; female 76% [37/49]) and 15 patients (median age [IQR] 17 [16-19]; male 80% [12/15]) participated. All parents and AYAs owned electronic tablets, smartphones, or both. Parents' most endorsed mHealth app features included a list of medications (71%, 35/49), information about 6-MP (71%, 35/49), refill reminders (71%, 35/49), and reminders to take 6-MP (71%, 35/49). AYAs' most endorsed features included refill reminders (73%, 11/15), reminders to take 6-MP (73%, 11/15), and tracking 6-MP (73%, 11/15). CONCLUSIONS: Parents and AYAs reported ubiquitous access to mobile technology and strong interest in multiple adherence-specific mHealth app features. Parents and AYAs provided valuable insight into preferred features for a multifunctional behavioral intervention (mHealth app) to promote medication adherence in pediatric ALL.","journal":"Journal of Medical Internet Research","year":2021,"id":165173,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":36,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.956,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":530784,"name":"Tasmeen Hussain","orcid":"0000-0003-4101-3687","position":1,"is_corresponding":false},{"id":625471,"name":"Leonardo Barrera","orcid":"0000-0001-9812-7883","position":2,"is_corresponding":false},{"id":688106,"name":"Stephanie W. Cai","orcid":"0000-0002-5617-2026","position":3,"is_corresponding":false},{"id":688107,"name":"Maureen Haugen","orcid":"0000-0002-3251-9478","position":4,"is_corresponding":false},{"id":688108,"name":"Elaine Morgan","orcid":"0000-0003-2505-8885","position":5,"is_corresponding":false},{"id":634416,"name":"Jenna Rossoff","orcid":"0000-0003-0471-9883","position":6,"is_corresponding":false},{"id":627803,"name":"Joanna Weinstein","orcid":"0000-0003-0585-9669","position":7,"is_corresponding":false},{"id":561562,"name":"Nobuko Hijiya","orcid":"0000-0002-0199-054X","position":8,"is_corresponding":false},{"id":232516,"name":"David Cella","orcid":"0000-0002-9881-4541","position":9,"is_corresponding":false},{"id":263623,"name":"Sherif M. Badawy","orcid":"0000-0002-4739-265X","position":10,"is_corresponding":false},{"id":298008,"name":"Mallorie B. Heneghan","orcid":"0000-0001-9454-0857","position":0,"is_corresponding":true}],"reference_count":43,"raw_metadata":null,"created_at":"2026-07-18T23:45:36.425208Z","pmid":"33599621","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}