{"doi":"10.2183/pjab.88.454","title":"Intra-abdominal fat area is a predictor for new onset of individual components of metabolic syndrome: MEtabolic syndRome and abdominaL ObesiTy (MERLOT study)","abstract":null,"journal":"Proceedings of the Japan Academy, Series B","year":2012,"id":619137,"datarank":0.586803450814222,"base_score":3.912023005428146,"endowment":3.912023005428146,"self_citation_contribution":0.586803450814222,"citation_network_contribution":0.0,"self_endowment_contribution":0.586803450814222,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":49,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1597630,"name":"Takashi MIYAWAKI","orcid":null,"position":1,"is_corresponding":false},{"id":1597631,"name":"Shinji YASUNO","orcid":null,"position":2,"is_corresponding":false},{"id":1597632,"name":"Kazuhiro NAKAO","orcid":null,"position":3,"is_corresponding":false},{"id":1597633,"name":"Sachiko TANAKA","orcid":null,"position":4,"is_corresponding":false},{"id":1597634,"name":"Midori IDA","orcid":null,"position":5,"is_corresponding":false},{"id":1597635,"name":"Masakazu HIRATA","orcid":null,"position":6,"is_corresponding":false},{"id":1597636,"name":"Masato KASAHARA","orcid":null,"position":7,"is_corresponding":false},{"id":177855,"name":"Kiminori HOSODA","orcid":null,"position":8,"is_corresponding":false},{"id":1597637,"name":"Kenji UESHIMA","orcid":null,"position":9,"is_corresponding":false},{"id":177858,"name":"Kazuwa NAKAO","orcid":null,"position":10,"is_corresponding":false},{"id":1597629,"name":"Yoko M. NAKAO","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Intra-abdominal fat area is a predictor for new onset of individual components of metabolic syndrome: MEtabolic syndRome and abdominaL ObesiTy (MERLOT study)","abstract":"OBJECTIVE: To investigate the significance of intra-abdominal fat area (IAFA) on new onset of individual components of the metabolic syndrome: high blood pressure, dyslipidemia, or hyperglycemia. METHODS: We conducted a longitudinal study using checkup data of a hospital from 1994 to 2010. Of 25,255 subjects, we examined 1,380 Japanese, who underwent computed tomography to measure IAFA and had no metabolic syndrome components at baseline. RESULTS: During 3.6 years of the mean follow-up period, one of metabolic syndrome components occurred in 752 subjects. Of three components, high blood pressure was more prevalent. The multiple Cox regression analysis disclosed that IAFA is significantly associated with onset of metabolic syndrome components (HR: 1.05 per 10 cm(2), 95%CI: 1.03-1.07). This finding was independent of BMI, and significant even in non-obese individuals with body mass index <25 kg/m(2). CONCLUSIONS: MERLOT study demonstrates that IAFA is an independent predictor for new onset of individual components of the metabolic syndrome, even in non-obese healthy Japanese.","is_dataset_classified":null,"base_score":3.912023005428146,"endowment":3.912023005428146,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"23060233","pmcid":"PMC3491080","openalex_id":"https://openalex.org/W2092430840","authors":[],"funders":[],"total_grants":0,"fwci":2.1361,"citation_percentile":0.87894407,"influential_citations":0,"citation_trend":[{"year":2013,"count":3},{"year":2014,"count":3},{"year":2015,"count":6},{"year":2016,"count":3},{"year":2017,"count":4},{"year":2018,"count":4},{"year":2019,"count":6},{"year":2020,"count":7},{"year":2021,"count":6},{"year":2022,"count":4},{"year":2023,"count":1},{"year":2026,"count":2}],"oa_status":"bronze","license":null,"oa_locations":[{"url":"https://www.jstage.jst.go.jp/article/pjab/88/8/88_PJA8808B-04/_pdf","host_type":"journal"},{"url":"https://www.jstage.jst.go.jp/article/pjab/88/8/88_PJA8808B-04/_pdf","host_type":"publisher"},{"url":"https://doi.org/10.2183/pjab.88.454","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/23060233","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3491080","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC3491080","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC3491080?pdf=render","host_type":"Europe_PMC"}],"fields_of_study":["Diabetes, Cardiovascular Risks, and Lipoproteins","Cardiovascular Disease and Adiposity","Adipokines, Inflammation, and Metabolic Diseases","Adult","Blood Pressure","Body Mass Index","Dyslipidemias","Female","Health","Humans","Hyperglycemia","Intra-Abdominal Fat","Japan","Kaplan-Meier Estimate","Longitudinal Studies","Male","Metabolic Syndrome","Middle Aged","Obesity, Abdominal","Proportional Hazards Models","Risk Factors","Tomography, X-Ray Computed","Young Adult"],"mesh_terms":["Adult","Blood Pressure","Female","Health","Humans","Hyperglycemia","Japan","Longitudinal Studies","Male","Middle Aged","Risk Factors","Tomography, X-Ray Computed","Body Mass Index","Proportional Hazards Models","Metabolic Syndrome","Intra-Abdominal Fat","Dyslipidemias","Kaplan-Meier Estimate","Young Adult","Obesity, Abdominal"],"keywords":["Metabolic syndrome","Abdominal obesity","Dyslipidemia","Medicine","Body mass index","Blood pressure","Internal medicine","Obesity","Longitudinal study","Proportional hazards model","Cardiology","Pathology"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-03T06:06:53.722344Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}