{"doi":"10.2169/internalmedicine.32.733","title":"Acquisition of CD13 and CD33 Expression at Relapse on Acute Myeloid Leukemia Cells with an Unusual Phenotype: MPO+CD13-CD33-.","abstract":null,"journal":"Internal Medicine","year":1993,"id":605127,"datarank":0.20794415416798362,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"self_citation_contribution":0.20794415416798362,"citation_network_contribution":0.0,"self_endowment_contribution":0.20794415416798362,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1552963,"name":"Yukinobu ICHIKAWA","orcid":null,"position":1,"is_corresponding":false},{"id":1552964,"name":"Nobumasa KOBAYASHI","orcid":null,"position":2,"is_corresponding":false},{"id":1552965,"name":"Ryuki FUKUDA","orcid":null,"position":3,"is_corresponding":false},{"id":1552966,"name":"Shuji YONEKURA","orcid":null,"position":4,"is_corresponding":false},{"id":1552967,"name":"Tadami NAGAO","orcid":null,"position":5,"is_corresponding":false},{"id":1552962,"name":"Hiroshi KAWADA","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Acquisition of CD13 and CD33 Expression at Relapse on Acute Myeloid Leukemia Cells with an Unusual Phenotype: MPO+CD13-CD33-.","abstract":"A case of acute myeloid leukemia (AML) with an unusual phenotype which was negative for a panel of myeloid antigens determined by flow cytometry, but was strongly positive for myeloperoxidase has recently been reported. We herein describe a case of AML with this unusual phenotype at diagnosis; relapse occurred with the acquisition of CD13 and CD33 expressions. Morphological features of the blasts at relapse seemed to be more compatible with myeloblasts than those at diagnosis. These phenotypic and morphological changes are suggestive of asynchronous differentiation, clonal evolution or clonal change of leukemic cells.","is_dataset_classified":null,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"7908235","pmcid":null,"openalex_id":"https://openalex.org/W2161080617","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.12666667,"influential_citations":0,"citation_trend":[],"oa_status":"bronze","license":null,"oa_locations":[{"url":"https://www.jstage.jst.go.jp/article/internalmedicine1992/32/9/32_9_733/_pdf","host_type":"journal"},{"url":"https://www.jstage.jst.go.jp/article/internalmedicine1992/32/9/32_9_733/_pdf","host_type":"publisher"},{"url":"http://www.jstage.jst.go.jp/article/internalmedicine1992/32/9/32_9_733/_pdf","host_type":"publisher"},{"url":"https://doi.org/10.2169/internalmedicine.32.733","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/7908235","host_type":"repository"}],"fields_of_study":["Acute Myeloid Leukemia Research","Immune cells in cancer","Hematopoietic Stem Cell Transplantation"],"mesh_terms":["Cell Differentiation","Humans","Male","Middle Aged","Peroxidase","Phenotype","Recurrence","Time Factors","Antigens, Differentiation, Myelomonocytic","Leukemia, Myeloid, Acute","Antigens, CD","CD13 Antigens","Sialic Acid Binding Ig-like Lectin 3"],"keywords":["CD33","Medicine","Phenotype","Myeloid leukemia","Myeloid","Myeloperoxidase","Immunology","Cancer research","Genetics","Gene","Biology","Stem cell","Inflammation"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-30T01:42:49.830061Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}