{"doi":"10.2169/internalmedicine.32.1","title":"Correlation of Nonspecific Bronchial Responsiveness to Baseline Pulmonary Function in Patients with Asthma and Sinobronchial Syndrome.","abstract":null,"journal":"Internal Medicine","year":1993,"id":683851,"datarank":0.29188652235829704,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.0,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1786471,"name":"Yumie KAMIO","orcid":null,"position":1,"is_corresponding":false},{"id":1786472,"name":"Takuma HASHIMOTO","orcid":null,"position":2,"is_corresponding":false},{"id":1786474,"name":"Tamotsu MATSUDA","orcid":null,"position":3,"is_corresponding":false},{"id":1786470,"name":"Masaki FUJIMURA","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Correlation of Nonspecific Bronchial Responsiveness to Baseline Pulmonary Function in Patients with Asthma and Sinobronchial Syndrome.","abstract":"To examine the relationship of nonspecific bronchial responsiveness to baseline pulmonary function, and to compare the reactivity in asthma and sinobronchitis, we measured the provocative concentration of methacholine, causing a 20% fall in forced expiratory volume in one second (PC20-FEV1) in 82 asthmatic patients, 54 patients with sinobronchial syndrome and 57 normal subjects. Log PC20-FEV1 was directly correlated to baseline pulmonary function. The strongest correlation was seen between log PC20-FEV1 and baseline FEV1 as a % of the predicted FEV1 (%FEV1), both in asthma (log PC20-FEV1 = 0.020 x %FEV1-1.988, r = 0.54, p < 0.01) and in sinobronchial syndrome (log PC20-FEV1 = 0.025 x %FEV1-1.233, r = 0.64, p < 0.01). From the regression equations, the mean value of PC20-FEV1 at 100% FEV1 was calculated as 1.02 and 18.5 mg/ml in asthmatic and sinobronchitic patients, respectively, and the value was 35.5 mg/ml in normal subjects. The PC20-FEV1 to %FEV1 relationship may be helpful to assess individually measured PC20-FEV1 values in patients with airway obstruction.","is_dataset_classified":null,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"8495036","pmcid":null,"openalex_id":"https://openalex.org/W2002393407","authors":[],"funders":[],"total_grants":0,"fwci":1.3225,"citation_percentile":0.80126239,"influential_citations":0,"citation_trend":[{"year":2016,"count":1}],"oa_status":"bronze","license":null,"oa_locations":[{"url":"https://www.jstage.jst.go.jp/article/internalmedicine1992/32/1/32_1_1/_pdf","host_type":"journal"},{"url":"https://www.jstage.jst.go.jp/article/internalmedicine1992/32/1/32_1_1/_pdf","host_type":"publisher"},{"url":"http://www.jstage.jst.go.jp/article/internalmedicine1992/32/1/32_1_1/_pdf","host_type":"publisher"},{"url":"https://doi.org/10.2169/internalmedicine.32.1","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/8495036","host_type":"repository"}],"fields_of_study":["Chronic Obstructive Pulmonary Disease (COPD) Research","Respiratory Support and Mechanisms","Asthma and respiratory diseases","Adult","Aged","Asthma","Bronchial Hyperreactivity","Bronchial Provocation Tests","Bronchitis","Female","Forced Expiratory Volume","Humans","Male","Methacholine Chloride","Middle Aged","Sinusitis","Syndrome"],"mesh_terms":["Adult","Aged","Asthma","Bronchial Provocation Tests","Bronchitis","Female","Forced Expiratory Volume","Humans","Male","Middle Aged","Sinusitis","Syndrome","Methacholine Chloride","Bronchial Hyperreactivity"],"keywords":["Medicine","Asthma","Methacholine","Pulmonary function testing","Internal medicine","Cardiology","Airway obstruction","Anesthesia","Airway","Respiratory disease","Lung"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T12:24:35.634960Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}