{"doi":"10.2147/opth.s399857","title":"Intraocular Lens Exchange: Indications, Comparative Outcomes by Technique, and Complications","abstract":"Purpose: To describe the indications, outcomes, and complications associated with intraocular lens (IOL) exchange. Patients and Methods: To determine the relative frequency of postoperative complications between techniques for all patients undergoing IOL exchange from May 1, 2014 through August 31, 2020. Results: IOL exchange was performed in 511 eyes of 489 patients (59.7% men; mean age: 67.0 ± 13.9 years, median time from cataract procedure to IOL exchange: 47.5 months). Mean uncorrected visual acuity significantly improved from 20/192 Snellen equivalent (logMAR 0.981) preoperatively to 20/61 (logMAR 0.487) at last follow-up ( P < 0.001). Overall, 384 eyes (78.7%) met their desired refractive outcome within ± 1.0 diopter (D). The most frequent complication was cystoid macular edema (CME) (n=39, 7.6%). Iris-sutured technique was associated with significantly greater frequency of subsequent IOL dislocation (10.3%) than 4-point scleral sutured (0%, P = 0.002), anterior chamber IOL (ACIOL, 1.5%, P = 0.01), and 2-point scleral sutured (0%, P = 0.03) techniques. Yamane scleral-fixation technique was associated with significantly greater frequency of developing IOL tilt (11.8%) than ACIOL (0%, P = 0.002), 4-point scleral sutured (1.1%, P = 0.01), 2-point scleral sutured (0%, P = 0.04), and iris-sutured (0%, P = 0.04) techniques. Conclusion: IOL exchange significantly improved uncorrected visual acuity and more than three-quarters of eyes met the refractive goal. Certain techniques were associated with complications, including subsequent dislocation associated with iris-sutured technique and IOL tilt associated with Yamane scleral-fixation technique. This information may help guide surgeons in deciding between procedural techniques for individual patients during IOL exchange preoperative planning. Keywords: intraocular lens, dislocation, Yamane, techniques, cataracts, complications","journal":"Clinical ophthalmology","year":2023,"id":328250,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":23,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8057,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":391213,"name":"Parastou Pakravan","orcid":"0000-0002-7799-9137","position":1,"is_corresponding":false},{"id":879870,"name":"James Lai","orcid":"0000-0003-1156-8120","position":2,"is_corresponding":false},{"id":288332,"name":"Arjun Watane","orcid":"0000-0003-2104-9949","position":3,"is_corresponding":false},{"id":308724,"name":"Divy Mehra","orcid":"0000-0002-9507-6635","position":4,"is_corresponding":false},{"id":516447,"name":"Tiffany Eatz","orcid":"0000-0003-3861-8335","position":5,"is_corresponding":false},{"id":337101,"name":"Nimesh A. Patel","orcid":"0000-0002-6681-6104","position":6,"is_corresponding":false},{"id":337102,"name":"Nicolas A. Yannuzzi","orcid":"0009-0004-0035-7373","position":7,"is_corresponding":false},{"id":337103,"name":"Jayanth Sridhar","orcid":"0000-0003-0910-057X","position":8,"is_corresponding":false},{"id":944360,"name":"Veshesh Patel","orcid":"0000-0003-2500-5214","position":0,"is_corresponding":true}],"reference_count":22,"raw_metadata":null,"created_at":"2026-07-19T01:08:52.196069Z","pmid":"36993987","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}