{"doi":"10.2147/copd.s388142","title":"COPD in People with HIV: Epidemiology, Pathogenesis, Management, and Prevention Strategies","abstract":null,"journal":"International Journal of Chronic Obstructive Pulmonary Disease","year":2023,"id":640157,"datarank":0.37273599746820013,"base_score":2.4849066497880004,"endowment":2.4849066497880004,"self_citation_contribution":0.37273599746820013,"citation_network_contribution":0.0,"self_endowment_contribution":0.37273599746820013,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":11,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1096108,"name":"Rebecca Abelman","orcid":"0000-0003-3040-1879","position":1,"is_corresponding":false},{"id":1663663,"name":"Crystal North","orcid":null,"position":2,"is_corresponding":false},{"id":1663664,"name":"Stephanie Christenson","orcid":null,"position":3,"is_corresponding":false},{"id":424013,"name":"Laurence Huang","orcid":"0000-0003-3888-2195","position":4,"is_corresponding":false},{"id":1663662,"name":"Katerina Byanova","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"COPD in People with HIV: Epidemiology, Pathogenesis, Management, and Prevention Strategies","abstract":"Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by airflow limitation and persistent respiratory symptoms. People with HIV (PWH) are particularly vulnerable to COPD development; PWH have demonstrated both higher rates of COPD and an earlier and more rapid decline in lung function than their seronegative counterparts, even after accounting for differences in cigarette smoking. Factors contributing to this HIV-associated difference include chronic immune activation and inflammation, accelerated aging, a predilection for pulmonary infections, alterations in the lung microbiome, and the interplay between HIV and inhalational toxins. In this review, we discuss what is known about the epidemiology and pathobiology of COPD among PWH and outline screening, diagnostic, prevention, and treatment strategies.","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"38050482","pmcid":"PMC10693779","openalex_id":null,"authors":[],"funders":[{"funder_name":"NHLBI NIH HHS","grant_id":"F32 HL166065","title":null},{"funder_name":"NHLBI NIH HHS","grant_id":"R01 HL128156","title":null},{"funder_name":"NIAID NIH HHS","grant_id":"T32 AI060530","title":null},{"funder_name":"NHLBI NIH HHS","grant_id":"K12 HL143961","title":null},{"funder_name":"NHLBI NIH HHS","grant_id":"K23 HL154863","title":null},{"funder_name":"NHLBI NIH HHS","grant_id":"R01 HL143998","title":null},{"funder_name":"National Institutes of Health","grant_id":"5T32AI060530-13","title":"Training in HIV Translational Research"},{"funder_name":"National Institutes of Health","grant_id":"5R01HL128156-08","title":"Inflammation, Aging, Microbes, Obstructive Lung Disease and Diffusion Abnormalities (I AM OLD-DA) Study"},{"funder_name":"National Institutes of Health","grant_id":"5K12HL143961-04","title":"UCSF Career Development Program in Cardiopulmonary, Hematologic, and Immunologic Comorbidities of HIV (CHIC)"},{"funder_name":"National Institutes of Health","grant_id":"1R01HL143998-01","title":"Integrated Analysis of Microbial and Genomic data in Obstructive Lung Disease (I AM GOLD) Study"},{"funder_name":"National Institutes of Health","grant_id":"5K23HL154863-05","title":"The influence of air pollution on lung health among people living with HIV."},{"funder_name":"National Institutes of Health","grant_id":"1F32HL166065-01","title":"Isolated Abnormality in the Diffusion Capacity for Carbon Monoxide in People Living with HIV – Epidemiology, Etiology and Pathogenesis"}],"total_grants":12,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"gold","license":"cc-by-nc","oa_locations":[{"url":"https://www.dovepress.com/getfile.php?fileID=94769","host_type":"publisher"},{"url":"https://www.dovepress.com/article/download/88590","host_type":"repository"},{"url":"https://escholarship.org/content/qt1nf8g5c2/qt1nf8g5c2.pdf","host_type":"repository"},{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10693779/pdf/copd-18-2795.pdf","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC10693779","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC10693779?pdf=render","host_type":"Europe_PMC"},{"url":"https://doi.org/10.2147/copd.s388142","host_type":""},{"url":"https://pubmed.ncbi.nlm.nih.gov/38050482","host_type":""},{"url":"http://dx.doi.org/10.2147/COPD.S388142","host_type":""},{"url":"https://www.dovepress.com/copd-in-people-with-hiv-epidemiology-pathogenesis-management-and-preve-peer-reviewed-fulltext-article-COPD","host_type":""},{"url":"https://escholarship.org/uc/item/1nf8g5c2","host_type":""},{"url":"https://doi.org/https://doi.org/10.2147/copd.s388142","host_type":""}],"fields_of_study":["03 medical and health sciences","0303 health sciences"],"mesh_terms":["Lung","Humans","HIV Infections","Pulmonary Disease, Chronic Obstructive","Inflammation","Risk Factors"],"keywords":["Tuberculosis","Air pollution","HIV","Smoking","COPD","Pulmonary infections","Immune Activation","Chronic Obstructive","Chronic Obstructive Pulmonary Disease","Immunology","Respiratory System","610","HIV Infections","Review","Cardiorespiratory Medicine and Haematology","International Journal of Chronic Obstructive Pulmonary Disease","Cardiovascular medicine and haematology","Pulmonary Disease","Pulmonary Disease, Chronic Obstructive","Clinical Research","Risk Factors","616","Tobacco","Humans","Lung","Inflammation","Biomedical and Clinical Sciences","Tobacco Smoke and Health","Prevention","Infectious Diseases","Good Health and Well Being","Medical Microbiology","Respiratory","HIV/AIDS","Sexually Transmitted Infections","Infection"],"sdg_mappings":[{"sdg_number":3,"sdg_label":"3. Good health"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"doi"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-07T07:07:50.886976Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}