{"doi":"10.21203/rs.3.rs-64910/v1","title":"Incidence and Time-Varying Predictors of HIV and Sexually Transmitted Infections Among Male Sex Workers in Mexico City","abstract":"Abstract Introduction : Male sex workers (MSWs) are at high-risk for HIV/STI acquisition. We quantified HIV/STI incidence rates and identified their time-varying predictors among MSWs in Mexico City. Methods : MSWs recruited from the largest HIV clinic and community sites in Mexico City were tested for chlamydia, gonorrhea, syphilis, hepatitis, and HIV at baseline, 6-months, and 12-months. Incidence rates with 95% bootstrapped confidence limits were calculated. We examined potential time-varying predictors using generalized estimating equations for a population averaged model. Results and Discussion : Among 227 MSWs, median age was 24 and baseline HIV prevalence was 32%. Incidence rates (per 100 person-years) were as follows: HIV (5.28; 95%CIs 2.52, 11.07), chlamydia (4.63; 95% 2.41, 8.90), gonorrhea (3.92; 95% 1.96, 7.84), syphilis (12.44; 95% 8.11, 19.08), hepatitis B (2.09; 95% 0.79, 5.58), hepatitis C (0.96; 95% 0.24, 3.85), any STI except HIV (17.61; 95% 12.51, 22.72), and any STI including HIV (19.93; 95%CI 14.78, 26.89). In the multivariable-adjusted model, incident STIs (excluding HIV) were lower among those who reported consistently using condoms during anal and vaginal intercourse (odds ratio (OR) = 0.03, 95% 0.00, 0.68) compared to those who reported inconsistently using condoms during anal and vaginal intercourse. Conclusions : HIV/STI incidence is high among MSWs in Mexico City. Consistent condom use is an important protective factor for HIV/STIs, and should be an important component of interventions to prevent incident infections.","journal":"Research Square","year":2020,"id":133705,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8145,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":369577,"name":"Marta Wilson‐Barthes","orcid":"0000-0002-9845-7142","position":1,"is_corresponding":false},{"id":523939,"name":"Andrew R. Zullo","orcid":"0000-0003-1673-4570","position":2,"is_corresponding":false},{"id":589669,"name":"Sandra G. Sosa‐Rubí","orcid":"0000-0001-7394-481X","position":3,"is_corresponding":false},{"id":589873,"name":"Carlos J. Conde‐Glez","orcid":null,"position":4,"is_corresponding":false},{"id":589670,"name":"Santa García-Cisneros","orcid":"0000-0002-2302-9100","position":5,"is_corresponding":false},{"id":529909,"name":"Mark N. Lurie","orcid":"0000-0002-3153-1715","position":6,"is_corresponding":false},{"id":270176,"name":"Brandon D. L. Marshall","orcid":"0000-0002-0134-7052","position":7,"is_corresponding":false},{"id":255176,"name":"Don Operario","orcid":"0000-0003-2467-5048","position":8,"is_corresponding":false},{"id":305156,"name":"Kenneth H. Mayer","orcid":"0000-0001-7460-733X","position":9,"is_corresponding":false},{"id":369579,"name":"Omar Galárraga","orcid":"0000-0002-9985-9266","position":10,"is_corresponding":false},{"id":589668,"name":"Karla Y. Ganley","orcid":"0000-0003-4872-1053","position":0,"is_corresponding":true}],"reference_count":32,"raw_metadata":null,"created_at":"2026-07-18T23:16:20.998822Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}