{"doi":"10.20944/preprints202502.1089.v1","title":"Functional Connectome Fingerprinting Through Tucker Tensor Decomposition","abstract":"The human functional connectome (FC) is a representation of the functional couplings between brain regions derived from blood oxygen level-dependent (BOLD) signals. We hypothesized that tensors, given their ability to project high-dimensional data into lower dimensional spaces via decomposition techniques, enable detecting the brain fingerprint with high accuracy. In this work, we present a mathematical framework based on Tucker decomposition to uncover the FC fingerprint of participants from the Young-Adult Human Connectome Project (HCP) Dataset. We analyzed how the following factors relate to within-and between-condition (rest-task) fingerprinting: brain parcellation granularity, decomposition rank, and scan length. Relative to FC matrices, we observed the highest increase in matching rates for parcellation granularity of 214 in the within-condition setting. Notably, our framework provides a substantial matching rate improvement in the between-condition setting relative to original FC matrices. Further, with our framework, sub-sampling the resting-state time series in the between-condition setting yielded fingerprinting results similar to those obtained by sampling the entire resting-state time series.","journal":"Preprints.org","year":2025,"id":562161,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9654,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":580068,"name":"Mintao Liu","orcid":null,"position":1,"is_corresponding":false},{"id":262626,"name":"Jaroslaw Harezlak","orcid":"0000-0002-3070-7686","position":2,"is_corresponding":false},{"id":1434270,"name":"Ana María Estrada Gómez","orcid":null,"position":3,"is_corresponding":false},{"id":385160,"name":"Joaquín Goñi","orcid":"0000-0003-3705-1955","position":4,"is_corresponding":false},{"id":1434269,"name":"V. E. de Carvalho","orcid":null,"position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T02:56:05.550545Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}