{"doi":"10.18061/ojph.v5i1.8514","title":"Health Disparities in Liver Cancer: An Analysis of the Ohio Cancer Incidence Surveillance System","abstract":"Background: We explored associations between neighborhood deprivation and tumor characteristics, treatment, and 5-year survival among primary hepatocellular carcinoma (HCC) patients in Ohio diagnosed between 2008 and 2016. Methods: We used data from the Ohio Cancer Incidence Surveillance System and limited our analysis to adult (>18 years of age) HCC patients with known census tract information based on address at diagnosis. Using principal components analysis, we created a neighborhood deprivation index (NDI) using 9 census tract-level variables. We examined associations between tumor characteristics (stage and tumor size) and NDI quintile using chi-square tests and analysis of variance (ANOVA). Associations between guideline-concordant care and NDI using log-binomial regression adjusted for sex, race, age at diagnosis, metropolitan status, cancer stage, and year of diagnosis were conducted. For 5-year survival, we utilized Cox proportional hazards models with a similar adjustment set. Results: Neighborhood deprivation index was not associated with stage or tumor size. Individuals living in the most deprived neighborhoods were 16% less likely to receive guideline-concordant care as compared to individuals living in the least deprived neighborhoods (adjusted prevalence ratio [PR]: 0.84; 95% confidence interval [CI]: 0.74-0.94). Similarly, individuals living in the most deprived neighborhoods were 15% less likely to survive 5 years compared to individuals living in the least deprived neighborhoods (adjusted Hazard Ratio: 1.15; 95% CI: 1.01-1.29). Conclusion: Our results suggest a negative association between neighborhood deprivation on guideline-concordant care and survival among HCC patients. Interventions targeting disparities of HCC should focus not only on individual-level factors but address larger neighborhood level factors as well.","journal":"Ohio Journal of Public Health","year":2022,"id":288583,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8131,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":361948,"name":"Rebecca Andridge","orcid":"0000-0001-9991-9647","position":1,"is_corresponding":false},{"id":272432,"name":"Shawnita Sealy–Jefferson","orcid":"0000-0002-8449-4903","position":2,"is_corresponding":false},{"id":505109,"name":"Ashley S. Felix","orcid":"0000-0001-8347-9018","position":3,"is_corresponding":false},{"id":675135,"name":"Robert B. Hood","orcid":"0000-0003-0078-301X","position":0,"is_corresponding":true}],"reference_count":25,"raw_metadata":null,"created_at":"2026-07-19T00:30:14.968626Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}