{"doi":"10.17615/pakr-g308","title":"Interruptions in HIV Prevention and Treatment During the COVID-19 Pandemic: A Cross-Sectional Study of Transgender and Gender Nonbinary Adults in the United States","abstract":"Background: Transgender and gender nonbinary (TNB) people have been disproportionately affected by HIV and the COVID-19 pandemic. This study explored the prevalence of HIV prevention and treatment (HPT) interruptions during the pandemic and identified factors associated with these interruptions. Setting: Data were drawn from LITE Connect, a US-based, nationwide, online, self-administered survey designed to examine the experiences of TNB adults during the COVID-19 pandemic. A convenience sample of 2134 participants were recruited between June 14, 2021, and May 1, 2022. Methods: The analytic sample was restricted to participants taking antiretroviral medications to prevent or treat HIV before the onset of the pandemic (n = 153). We calculated descriptive statistics as well as Pearson χ2 bivariate tests and multivariable models to identify factors associated with HPT interruptions during the pandemic. Results: Thirty-nine percent of participants experienced an HPT interruption. We found a lower odds of HPT interruptions among participants living with HIV [adjusted odds ratios (aOR) 0.45; 95% Confidence Intervals (CI): 0.22, 0.92; P = 0.02] and essential workers [aOR 0.49; 95% CI: 0.23, 1.0; P = 0.06] and higher odds among people with chronic mental health conditions [aOR 2.6; 95% CI: 1.1, 6.2; P = 0.03]. When sex and education were included, we found a lower odds of interruptions among people with higher education. CI widened, but the magnitude and direction of effects did not change for the other variables. Conclusions: Focused strategies to address longstanding psychosocial and structural inequities are needed to mitigate HPT treatment interruptions in TNB people and prevent similar challenges during future pandemics.","journal":"UNC Libraries","year":2024,"id":500333,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.86,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":390637,"name":"Trang Quynh Nguyen","orcid":"0000-0003-1653-5491","position":1,"is_corresponding":false},{"id":1149969,"name":"Jennifer Williams","orcid":"0000-0002-9037-3999","position":2,"is_corresponding":false},{"id":958660,"name":"Carmen Gutiérrez","orcid":"0000-0001-9256-4468","position":3,"is_corresponding":false},{"id":1149967,"name":"Sabriya Linton","orcid":"0000-0003-3579-2151","position":4,"is_corresponding":false},{"id":952366,"name":"Ashleigh J. Rich","orcid":"0000-0003-3742-7086","position":5,"is_corresponding":false},{"id":1031964,"name":"Dee Adams","orcid":"0000-0002-1012-0191","position":6,"is_corresponding":false},{"id":433597,"name":"Marissa A. Miller","orcid":"0000-0003-2432-7027","position":7,"is_corresponding":false},{"id":394627,"name":"Andrea L. Wirtz","orcid":"0000-0002-2063-1534","position":8,"is_corresponding":false},{"id":277262,"name":"Sari L. Reisner","orcid":"0000-0001-7868-4746","position":9,"is_corresponding":false},{"id":284815,"name":"Tonia Poteat","orcid":"0000-0001-6541-3787","position":10,"is_corresponding":false},{"id":1149968,"name":"Carter Brown","orcid":"0000-0002-4591-993X","position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:10:08.435215Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}