{"doi":"10.17615/nnk8-vz92","title":"Correction: Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry","abstract":"Adult height is a classic polygenic trait of high heritability (h 2 ∼0.8). More than 180 single nucleotide polymorphisms (SNPs), identified mostly in populations of European descent, are associated with height. These variants convey modest effects and explain ∼10% of the variance in height. Discovery efforts in other populations, while limited, have revealed loci for height not previously implicated in individuals of European ancestry. Here, we performed a meta-analysis of genome-wide association (GWA) results for adult height in 20,427 individuals of African ancestry with replication in up to 16,436 African Americans. We found two novel height loci (Xp22-rs12393627, P = 3.4×10−12 and 2p14-rs4315565, P = 1.2×10−8). As a group, height associations discovered in European-ancestry samples replicate in individuals of African ancestry (P = 1.7×10−4 for overall replication). Fine-mapping of the European height loci in African-ancestry individuals showed an enrichment of SNPs that are associated with expression of nearby genes when compared to the index European height SNPs (P<0.01). Our results highlight the utility of genetic studies in non-European populations to understand the etiology of complex human diseases and traits.","journal":"UNC Libraries","year":2021,"id":230450,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9401,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":611794,"name":"Angela Britton","orcid":null,"position":1,"is_corresponding":false},{"id":299670,"name":"Jennifer J. Hu","orcid":"0000-0002-0021-5699","position":2,"is_corresponding":false},{"id":294550,"name":"Christine B. Ambrosone","orcid":"0000-0003-1717-9943","position":3,"is_corresponding":false},{"id":579070,"name":"Larry D. Atwood","orcid":null,"position":4,"is_corresponding":false},{"id":55292,"name":"Ellen W. Demerath","orcid":"0000-0002-4585-4064","position":5,"is_corresponding":false},{"id":21712,"name":"Cameron D. Palmer","orcid":"0000-0003-3130-1968","position":6,"is_corresponding":false},{"id":6558,"name":"Esther M. John","orcid":"0000-0003-3259-8003","position":7,"is_corresponding":false},{"id":6431,"name":"Stephen J. Chanock","orcid":"0000-0002-2324-3393","position":8,"is_corresponding":false},{"id":836932,"name":"Véronique Adoue","orcid":null,"position":9,"is_corresponding":false},{"id":108723,"name":"Jingzhong Ding","orcid":null,"position":10,"is_corresponding":false},{"id":49827,"name":"Brendan J. Keating","orcid":"0000-0002-3320-3723","position":11,"is_corresponding":false},{"id":245381,"name":"Eric Boerwinkle","orcid":"0000-0001-8813-0544","position":12,"is_corresponding":false},{"id":130786,"name":"Sandra L. Deming","orcid":null,"position":13,"is_corresponding":false},{"id":21837,"name":"Bamidele O. Tayo","orcid":"0000-0002-2277-3958","position":14,"is_corresponding":false},{"id":836148,"name":"Amidou N’Diaye","orcid":"0000-0001-7769-7801","position":15,"is_corresponding":false},{"id":836149,"name":"Craig Johnson","orcid":"0000-0002-8552-6962","position":16,"is_corresponding":false},{"id":21711,"name":"Michael A. Nalls","orcid":null,"position":17,"is_corresponding":false},{"id":51469,"name":"Bing Ge","orcid":"0000-0003-2527-5580","position":18,"is_corresponding":false},{"id":299776,"name":"Leslie Bernstein","orcid":"0000-0002-7692-6518","position":19,"is_corresponding":false},{"id":346907,"name":"Tamara B. 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Ingles","orcid":"0000-0001-9181-8745","position":29,"is_corresponding":false},{"id":52674,"name":"Dena G. Hernandez","orcid":null,"position":30,"is_corresponding":false},{"id":231134,"name":"Adebowale Adeyemo","orcid":"0000-0002-3105-3231","position":31,"is_corresponding":false},{"id":21996,"name":"Caroline S. Fox","orcid":null,"position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-18T23:55:05.844766Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}