{"doi":"10.17615/mqrb-k695","title":"The Health of HIV-exposed Children after Early Weaning","abstract":"There are potential health risks associated with the use of early weaning to prevent mother-to-child transmission of HIV in resource-poor settings. Our objective was to examine growth and nutrient inadequacies among a cohort of children weaned early. Children participating in the Breastfeeding Antiretrovirals and Nutrition (BAN) Study in Lilongwe, Malawi, had HIV-infected mothers, were weaned at 6 months and fed LNS until 12 months. 40 HIV-negative, BAN-exited children were compared to 40 HIV-negative, community children matched on age, gender and local health clinic. Nutrient intake was calculated from 24-hour dietary recalls collected from BAN-exited children. Anthropometric measurements were collected from BAN-exited and matched community children at 15-16 months, and 2 months later. Longitudinal random effects sex-stratified models were used to evaluate anthropometric differences between the 2 groups. BAN-exited children consumed adequate energy, protein, and carbohydrates but inadequate amounts of fat. The prevalence of inadequate micronutrient intakes were: 46% for vitamin A; 20% for vitamin B6; 69% for folate; 13% for vitamin C; 19% for iron; 23% for zinc. Regarding growth, BAN-exited girls gained weight at a significantly lower rate (0.02g/kg/day [95%CI: 0.01, 0.03] than their matched comparison (0.05g/kg/day [95%CI: 0.03, 0.07]); BAN girls grew significantly slower (0.73cm/month [95%CI: 0.40,1.06]) than their matched comparison (1.55cm/month [95%CI: 0.98, 2.12]). Among this sample of BAN-exited children, early weaning was associated with dietary deficiencies and girls experienced reduced growth velocity. In resource-poor settings, HIV prevention programs must ensure that breastfeeding stop only once a nutritionally adequate and safe diet without breastmilk can be provided.","journal":"UNC Libraries","year":2020,"id":117272,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9561,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":544835,"name":"Charles M. van der Horst","orcid":null,"position":1,"is_corresponding":false},{"id":294983,"name":"Sascha Ellington","orcid":"0000-0002-5584-5006","position":2,"is_corresponding":false},{"id":546828,"name":"Charles Chasela","orcid":"0000-0001-8362-5986","position":3,"is_corresponding":false},{"id":547524,"name":"Martin Tembo","orcid":null,"position":4,"is_corresponding":false},{"id":547525,"name":"Alice Soko","orcid":null,"position":5,"is_corresponding":false},{"id":460381,"name":"Francis Martinson","orcid":null,"position":6,"is_corresponding":false},{"id":547526,"name":"Chimwemwe Mkhomawanthu","orcid":null,"position":7,"is_corresponding":false},{"id":546829,"name":"Ellen Piwoz","orcid":"0000-0002-2018-6645","position":8,"is_corresponding":false},{"id":273917,"name":"Denise J. Jamieson","orcid":"0000-0003-2597-1201","position":9,"is_corresponding":false},{"id":546830,"name":"Megan Parker","orcid":"0000-0003-0260-9445","position":10,"is_corresponding":false},{"id":324211,"name":"Linda S. Adair","orcid":"0000-0002-3670-8073","position":11,"is_corresponding":false},{"id":546831,"name":"Dumbani Kayira","orcid":"0000-0002-7772-8070","position":12,"is_corresponding":false},{"id":366918,"name":"Margaret E. Bentley","orcid":"0000-0002-1220-0208","position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-18T23:13:51.309289Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}