{"doi":"10.17615/j9hs-ax36","title":"TIR-only protein RBA1 recognizes a pathogen effector to regulate cell death in Arabidopsis","abstract":"Multicellular organisms must have complex immune systems to detect and defeat pathogens. Plants rely on nucleotide binding site leucine rich repeat (NLR) intracellular receptors to detect pathogens. For hundreds of years, plant breeders have selected for disease-resistance traits derived from NLR genes. Despite the molecular cloning of the first NLRs more than 20 y ago, we still do not understand how these sensors function at a mechanistic level. Here, we identified a truncated NLR protein that activates cell death in response to a specific pathogen effector. Understanding how truncated NLRs function will provide a better mechanistic understanding of the plant immune system and an expanded toolkit with which to engineer disease resistance rationally in crops.","journal":"UNC Libraries","year":2020,"id":109647,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":9,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9519,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":18791,"name":"Marc T. Nishimura","orcid":"0000-0003-4666-6900","position":1,"is_corresponding":false},{"id":30207,"name":"Eui-Hwan Chung","orcid":null,"position":2,"is_corresponding":false},{"id":30208,"name":"Farid El Kasmi","orcid":"0000-0002-4634-7689","position":3,"is_corresponding":false},{"id":30209,"name":"Michael Hyunh","orcid":null,"position":4,"is_corresponding":false},{"id":30210,"name":"Erin Osborne Nishimura","orcid":"0000-0002-4313-4573","position":5,"is_corresponding":false},{"id":18795,"name":"Jeffery L. Dangl","orcid":"0000-0003-3199-8654","position":6,"is_corresponding":false},{"id":30214,"name":"John Sondek","orcid":"0000-0002-1127-8310","position":7,"is_corresponding":false},{"id":30201,"name":"Ryan G. Anderson","orcid":"0000-0003-3219-7680","position":8,"is_corresponding":false},{"id":30203,"name":"Terry F. Law","orcid":null,"position":9,"is_corresponding":false},{"id":30205,"name":"Mischa Machius","orcid":"0000-0002-6040-1362","position":10,"is_corresponding":false},{"id":30204,"name":"Qingli L. Liu","orcid":null,"position":11,"is_corresponding":false},{"id":30212,"name":"Karen Cherkis","orcid":null,"position":12,"is_corresponding":false},{"id":30206,"name":"Zachary L. Nimchuk","orcid":"0000-0003-1826-0671","position":13,"is_corresponding":false},{"id":449741,"name":"Li Yang","orcid":"0000-0002-5484-0895","position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-18T23:12:54.309019Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}