{"doi":"10.17615/e8a4-t829","title":"Genetic predisposition to obesity is associated with asthma in US Hispanics/Latinos: Results from the Hispanic Community Health Study/Study of Latinos","abstract":"Obesity and asthma are two significant public health issues worldwide. Accumulating evidence has related high body mass index (BMI) and obesity with asthma, although a causal role of obesity in the development of asthma remains uncertain. A recent study reported a significant association between genetic predisposition to obesity, estimated by a genetic risk score (GRS) based on 32 BMI-associated variants, and increased risk of childhood asthma in 4,835 European children, supporting a potential causal relationship between obesity and asthma. However, it remains unknown whether genetic predisposition to obesity is associated with later-onset asthma which is different from childhood-onset asthma. Data is also limited in other ethnic groups, especially in US Hispanics/Latinos who have both high prevalence of obesity and asthma. Therefore, we aimed to examine whether genetic predisposition to obesity is associated with asthma and explore potential differences by sex and age of asthma onset in U.S. Hispanics/Latinos.","journal":"UNC Libraries","year":2024,"id":499121,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9568,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":599808,"name":"Robert M. Kaplan","orcid":"0000-0003-4837-5330","position":1,"is_corresponding":false},{"id":487225,"name":"Sharmilee M. Nyenhuis","orcid":"0000-0002-7381-9733","position":2,"is_corresponding":false},{"id":440455,"name":"Deepa Rastogi","orcid":"0000-0001-5714-9250","position":3,"is_corresponding":false},{"id":980420,"name":"C.C. Laurie","orcid":null,"position":4,"is_corresponding":false},{"id":218544,"name":"Jee‐Young Moon","orcid":"0000-0001-9218-8335","position":5,"is_corresponding":false},{"id":526168,"name":"Q. Qi","orcid":null,"position":6,"is_corresponding":false},{"id":526071,"name":"K.E. North","orcid":null,"position":7,"is_corresponding":false},{"id":854530,"name":"Yue Leon Guo","orcid":"0000-0002-8530-4809","position":8,"is_corresponding":false},{"id":835798,"name":"L.A.P. Sanchez-Johnsen","orcid":null,"position":9,"is_corresponding":false},{"id":538012,"name":"Bing Yu","orcid":"0000-0001-6605-6742","position":10,"is_corresponding":false},{"id":549707,"name":"Sonia M. Davis","orcid":null,"position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-19T02:09:45.971055Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}