{"doi":"10.17615/9f37-cy93","title":"The influence of exposure to maternal diabetes in utero on the rate of decline in β-cell function among youth with diabetes","abstract":"A relationship between exposure to maternal diabetes in utero and a younger age at diagnosis of type 2 diabetes was detected in SEARCH for Diabetes in Youth Study, while no significant association was detected with paternal diabetes status, suggesting an independent effect of the intrauterine exposure to hyperglycemia. We assessed the influence of exposure to maternal diabetes in utero on beta cell decline measured using fasting C-peptide (FCP) among 1079 youth with diabetes, including 941 with type 1 and 138 with type 2, who were followed post-diagnosis for an average of 58 months. No significant relationship was detected between exposure to maternal diabetes in utero and change in FCP levels in youth with type 1 or type 2 diabetes. These findings suggest that exposure to maternal diabetes in utero may not be an important determinant of short-term beta-cell function decline in youth with type 1 or type 2 diabetes.","journal":"UNC Libraries","year":2020,"id":144449,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9584,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":612931,"name":"David J. Pettitt","orcid":"0000-0002-0398-7088","position":1,"is_corresponding":false},{"id":43418,"name":"Ralph B. D’Agostino","orcid":"0000-0002-3550-8395","position":2,"is_corresponding":false},{"id":368465,"name":"Tessa Crume","orcid":"0000-0002-5397-4154","position":3,"is_corresponding":false},{"id":339660,"name":"Elizabeth J. Mayer‐Davis","orcid":"0000-0003-3858-0517","position":4,"is_corresponding":false},{"id":249641,"name":"Dana Dabelea","orcid":"0000-0001-9514-8929","position":5,"is_corresponding":false},{"id":342441,"name":"Jean M. Lawrence","orcid":"0000-0002-2480-8480","position":6,"is_corresponding":false},{"id":515768,"name":"Jeanette S. Andrews","orcid":null,"position":7,"is_corresponding":false},{"id":420327,"name":"Lawrence M. Dolan","orcid":"0000-0002-5359-0636","position":8,"is_corresponding":false},{"id":533461,"name":"Beatriz L. Rodríguez","orcid":"0000-0002-6728-7718","position":9,"is_corresponding":false},{"id":600784,"name":"Jennifer Law","orcid":"0000-0001-9956-7178","position":10,"is_corresponding":false},{"id":265850,"name":"Sharon Saydah","orcid":"0000-0002-6350-5300","position":11,"is_corresponding":false},{"id":71415,"name":"Carla J. Greenbaum","orcid":"0000-0003-4451-9800","position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-18T23:17:45.339291Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}