{"doi":"10.17615/7j39-7m19","title":"Unsuspected Dengue Causes Acute Febrile Illness in Rural and Semi-Urban Southern Sri Lanka","abstract":"Acute dengue may be under-recognized in other regions because of limited studies and tools for rapid diagnosis.Dengue virus (DENV), a globally emerging cause of undifferentiated fever, has been documented in the heavily urbanized western coast of Sri Lanka since the 1960s. New areas of Sri Lanka are now being affected, and the reported number and severity of cases have increased. To study emerging DENV in southern Sri Lanka, we obtained epidemiologic and clinical data and acute- and convalescent-phase serum samples from patients >2 years old with febrile illness. We tested paired serum samples for DENV IgG and IgM and serotyped virus by using isolation and reverse transcription PCR. We identified acute DENV infection (serotypes 2, 3, and 4) in 54 (6.3%) of 859 patients. Only 14% of patients had clinically suspected dengue; however, 54% had serologically confirmed acute or past DENV infection. DENV is a major and largely unrecognized cause of fever in southern Sri Lanka, especially in young adults.","journal":"UNC Libraries","year":2020,"id":136759,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9602,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2020-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":595877,"name":"John J. Strouse","orcid":"0000-0003-0341-1457","position":1,"is_corresponding":false},{"id":517315,"name":"Vasantha Devasiri","orcid":"0000-0002-2193-9995","position":2,"is_corresponding":false},{"id":500318,"name":"Megan E. Reller","orcid":null,"position":3,"is_corresponding":false},{"id":33039,"name":"Christopher W. Woods","orcid":"0000-0001-7240-2453","position":4,"is_corresponding":false},{"id":596527,"name":"Wasantha Kodikara-Arachichi","orcid":null,"position":5,"is_corresponding":false},{"id":105519,"name":"Aravinda de Silva","orcid":null,"position":6,"is_corresponding":false},{"id":596528,"name":"Bodinayake, Champika","orcid":null,"position":7,"is_corresponding":false},{"id":588635,"name":"Anne Broadwater","orcid":null,"position":8,"is_corresponding":false},{"id":517313,"name":"Ajith Nagahawatte","orcid":"0000-0001-6481-0203","position":9,"is_corresponding":false},{"id":258282,"name":"Truls Østbye","orcid":"0000-0002-0662-7440","position":0,"is_corresponding":true}],"reference_count":0,"raw_metadata":null,"created_at":"2026-07-18T23:16:52.487376Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}