{"doi":"10.15857/ksep.2021.00661","title":"Creatine Kinase and Lactate Dehydrogenase Enzymes Response to Lactate Tolerance Exercise Test","abstract":"<jats:p>PURPOSE: This study aimed to assess alterations in serum creatine kinase (CK) and lactate dehydrogenase (LDH) levels after performing a lactate tolerance exercise test (LTET) in elite male swimmers.METHODS: Fourteen male adolescent swimmers participated in this study. All subjects performed LTET (8×100-meter swimming) with a 1-minute recovery interval between eight trainings. Plasma CK and LDH (markers of muscle damage) levels were measured 30 minute before and 24 hours after the test. A paired t-test was used for statistical analysis of data.RESULTS: Plasma CK and LDH levels increased immediately after LTET as compared to the values 30 minutes prior to exercise (188.91±34.04 vs. 148.83±29.63 mg/dL, p=.029; 318.17±53.89 vs. 272.08±52.93 mg/dL, p=.010, respectively). Both CK and LDH levels displayed a decreasing trend 24 hours post-LTET; however, there was no significant difference immediately after the test.CONCLUSIONS: Plasma CK and LDH levels increased following LTET, which is representative of muscle damage.</jats:p>","journal":"Exercise Science","year":2022,"id":600157,"datarank":0.29188652235829704,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"self_citation_contribution":0.29188652235829704,"citation_network_contribution":0.0,"self_endowment_contribution":0.29188652235829704,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":6,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1538426,"name":"Farhang Hooshmand","orcid":"0000-0002-6605-5464","position":1,"is_corresponding":false},{"id":1538427,"name":"Masihollah Shakeri","orcid":"0000-0001-9184-9912","position":2,"is_corresponding":false},{"id":1538428,"name":"Vahid Rahmanian","orcid":"0000-0003-3460-7495","position":3,"is_corresponding":false},{"id":1538429,"name":"Fatemeh Sotoodeh Jahromi","orcid":"0000-0001-9293-4158","position":4,"is_corresponding":false},{"id":1538430,"name":"Abdolreza Sotoodeh Jahromi","orcid":"0000-0002-2131-2113","position":5,"is_corresponding":false},{"id":1538425,"name":"Karamatollah Rahmanian","orcid":"0000-0003-3324-7651","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Creatine Kinase and Lactate Dehydrogenase Enzymes Response to Lactate Tolerance Exercise Test","abstract":"<jats:p>PURPOSE: This study aimed to assess alterations in serum creatine kinase (CK) and lactate dehydrogenase (LDH) levels after performing a lactate tolerance exercise test (LTET) in elite male swimmers.METHODS: Fourteen male adolescent swimmers participated in this study. All subjects performed LTET (8×100-meter swimming) with a 1-minute recovery interval between eight trainings. Plasma CK and LDH (markers of muscle damage) levels were measured 30 minute before and 24 hours after the test. A paired t-test was used for statistical analysis of data.RESULTS: Plasma CK and LDH levels increased immediately after LTET as compared to the values 30 minutes prior to exercise (188.91±34.04 vs. 148.83±29.63 mg/dL, p=.029; 318.17±53.89 vs. 272.08±52.93 mg/dL, p=.010, respectively). Both CK and LDH levels displayed a decreasing trend 24 hours post-LTET; however, there was no significant difference immediately after the test.CONCLUSIONS: Plasma CK and LDH levels increased following LTET, which is representative of muscle damage.</jats:p>","is_dataset_classified":null,"base_score":1.9459101490553132,"endowment":1.9459101490553132,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"23304386","pmcid":null,"openalex_id":"https://openalex.org/W4225272876","authors":[],"funders":[],"total_grants":0,"fwci":0.5007,"citation_percentile":0.64072711,"influential_citations":0,"citation_trend":[{"year":2022,"count":1},{"year":2024,"count":1},{"year":2025,"count":3},{"year":2026,"count":1}],"oa_status":"gold","license":"cc-by-nc","oa_locations":[{"url":"https://www.ksep-es.org/upload/pdf/ksep-2021-00661.pdf","host_type":"journal"},{"url":"https://www.ksep-es.org/upload/pdf/ksep-2021-00661.pdf","host_type":"publisher"},{"url":"http://ksep-es.org/upload/pdf/ksep-2021-00661.pdf","host_type":"publisher"},{"url":"http://ksep-es.org/journal/view.php?doi=10.15857/ksep.2021.00661","host_type":"publisher"},{"url":"https://doi.org/10.15857/ksep.2021.00661","host_type":"journal"},{"url":"https://doaj.org/article/a9a017d6be1d4cad9834ba1eadcc3fac","host_type":"repository"}],"fields_of_study":["Exercise and Physiological Responses","Sports Performance and Training","Cardiovascular and exercise physiology"],"mesh_terms":[],"keywords":["Lactate dehydrogenase","Creatine kinase","Muscle damage","Internal medicine","Creatine","Medicine","Endocrinology","Chemistry","Enzyme","Biochemistry"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Life below water"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-29T12:21:26.414329Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}