{"doi":"10.15761/cmid.1000194","title":"In silico drug repurposing to combat COVID-19 based on pharmacogenomics of patient transcriptomic data","abstract":"Researchers are also exploring targeting the host receptors of SARS-CoV-2 as another potential solution. Inhibitors of the two main receptors for SARS-CoV-2/SARS-CoV-1 entry in human cells, ACE2 and TMPRSS2, are being tested as potential treatment options A recent study published, other host interacting proteins have been curated from previously published literature In addition, a list of 332 high-confidence interactions between SARS-CoV-2 and human proteins was recently published by Gordon et al., who used affinity purification mass spectrometry on a human cell line expressing the viral proteins","journal":"Clinical Microbiology and Infectious Diseases","year":2021,"id":208067,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.8869,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2021-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":254789,"name":"Kevin Camphausen","orcid":"0000-0002-0450-4877","position":1,"is_corresponding":false},{"id":427981,"name":"Uma Shankavaram","orcid":"0000-0001-9659-0284","position":2,"is_corresponding":false},{"id":542705,"name":"Shaoli Das","orcid":"0000-0002-3428-1862","position":0,"is_corresponding":true}],"reference_count":34,"raw_metadata":null,"created_at":"2026-07-18T23:51:53.662668Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}