{"doi":"10.1556/2006.2024.00068","title":"The longitudinal association between reward processing and symptoms of video game addiction in the Adolescent Brain Cognitive Development Study","abstract":"Background and aims: Video games are a common form of entertainment in adolescents, which may result in gaming habits characterized by impairment to reward-related decision-making. The aim of the current study was to investigate the relationship between reward processing and symptoms of gaming addiction in adolescents. Methods: Data from three consecutive follow-up years (years 2, 3 and 4) of the Adolescent Brain Cognitive Development (ABCD) Study were analyzed (n = 6,143, total observations = 12,745, mean age at year-2 = 12 years). Participants completed the Video Game Addiction Questionnaire (VGAQ) at each visit. Discrete stages of reward processing were measured at the year-2 visit using the Monetary Incentive Delay task while the participant completed a functional magnetic resonance imaging (fMRI) scan. Bayesian hierarchical linear models were employed to examine the longitudinal association between reward processing in regions of interest at year-2 and VGAQ scores over time. Results: Lower activation in the bilateral caudate during the anticipation of a large reward (β = -0.87, 95% CI: -1.68, -0.07) was associated with greater VGAQ scores over time. This implies that for each one-unit increase in brain activity in the caudate, there was an associated 0.87-point decrease in symptoms of gaming addiction as measured by the VGAQ. No association was found between reward feedback and VGAQ scores. Discussion and Conclusions: The findings suggest that abnormal reward processing in the caudate nucleus is associated with symptoms of gaming addiction in adolescents. These results provide a clearer understanding of the brain mechanisms involved in gaming addiction, which could inform future preventive and therapeutic strategies.","journal":"Journal of Behavioral Addictions","year":2024,"id":443837,"datarank":0.40364495899526276,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"self_citation_contribution":0.32958368660043297,"citation_network_contribution":0.07406127239482976,"self_endowment_contribution":0.32958368660043297,"citer_contribution":0.07406127239482976,"corpus_percentile":54.49833681441943,"corpus_rank":5883,"citation_count":8,"citer_count":7,"citers_with_citation_signal":5,"citers_with_endowment":5,"datacite_reuse_total":0,"is_dataset":true,"is_dataset_confidence":0.674,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":388141,"name":"John J. Foxe","orcid":"0000-0002-4300-3098","position":1,"is_corresponding":false},{"id":333978,"name":"Edwin van Wijngaarden","orcid":"0000-0001-7583-4630","position":2,"is_corresponding":false},{"id":79256,"name":"Wesley K. Thompson","orcid":"0000-0002-1148-1976","position":3,"is_corresponding":false},{"id":388142,"name":"Edward G. Freedman","orcid":"0000-0001-8570-6325","position":4,"is_corresponding":false},{"id":621612,"name":"Daniel A. Lopez","orcid":"0000-0002-7358-2609","position":0,"is_corresponding":true}],"reference_count":96,"raw_metadata":null,"created_at":"2026-07-19T02:01:29.001453Z","pmid":"39656219","pmcid":"PMC11737415","fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}