{"doi":"10.1556/038.54.2019.013","title":"Insecticide Toxicity, Synergism and Resistance in Plutella xylostella (Lepidoptera: Plutellidae)","abstract":"<jats:p>\n          <jats:italic>Plutella xylostella</jats:italic> has become particularly notorious for its\n                    resistance to various insecticides. The toxicities of abamectin, hexaflumuron\n                    and indoxacarb to third instar larvae of the pest were assayed using the\n                    leaf-dipping method. The results showed that abamectin and indoxacarb with the\n                    lowest LC50 values exhibited stronger toxicity to larvae than hexaflumuron. To\n                    determine the synergism of PBO, DEM, DEF and TPP on the toxicity of tested\n                    insecticides and demonstrating possible biochemical mechanisms, an abamectin-, a\n                    hexaflu-muron- and an indoxacarb-resistant strain of <jats:italic>P.\n                        xylostella</jats:italic> were selected under laboratory conditions. After 10\n                    generations of selection, the selected strains developed 14.21, 7.08, and\n                    32.36-fold higher resistance to these insecticides, respectively. Abamectin\n                    resistance in abamectin-selected strain was suppressed with the synergists such\n                    as DEM and PBO, suggesting the involvement of monooxygeneses and glutathione\n                    S-transferase in the development of resistance in <jats:italic>P.\n                    xylostella</jats:italic>. Treatment with PBO and DEF significantly decreased the\n                    toxicity of hexaflumuron in the hexaflumuron-selected strain. Also, in\n                    indoxacarb-selected strain, the maximum synergism was occurred using PBO and\n                    DEF, followed by DEM and TPP. Hexaflumuron and indoxacarb synergism studies\n                    indicated in hexaflumuron resistance, monooxygenases and esterases, and in\n                    indoxacarb resistance, monooxygenases, esterases and glutathione S-transferae\n                    may be involved in the resistance mechanisms</jats:p>","journal":"Acta Phytopathologica et Entomologica Hungarica","year":2019,"id":37304,"datarank":0.36779092856497575,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"self_citation_contribution":0.24141568686511508,"citation_network_contribution":0.12637524169986067,"self_endowment_contribution":0.24141568686511508,"citer_contribution":0.12637524169986067,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":4,"citers_with_citation_signal":3,"citers_with_endowment":3,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":187226,"name":"F. Khorrami","orcid":null,"position":1,"is_corresponding":false},{"id":187227,"name":"M. Forouzan","orcid":null,"position":2,"is_corresponding":false},{"id":187225,"name":"A. Soleymanzade","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":1.6094379124341003,"endowment":1.6094379124341003,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"24523987","pmcid":null,"openalex_id":"https://openalex.org/W2956023258","authors":[],"funders":[],"total_grants":0,"fwci":0.1709,"citation_percentile":0.52510001,"influential_citations":0,"citation_trend":[{"year":2020,"count":1},{"year":2021,"count":1},{"year":2023,"count":1},{"year":2025,"count":1}],"oa_status":"closed","license":null,"oa_locations":[{"url":"https://akjournals.com/view/journals/038/54/1/article-p147.xml","host_type":"publisher"},{"url":"https://akjournals.com/downloadpdf/journals/038/54/1/article-p147.xml","host_type":"publisher"},{"url":"https://doi.org/10.1556/038.54.2019.013","host_type":"journal"}],"fields_of_study":["Insect Resistance and Genetics","Insect-Plant Interactions and Control","Insect Pest Control Strategies","Biology","Environmental Science"],"mesh_terms":[],"keywords":["Indoxacarb","Abamectin","Plutellidae","Plutella","Biology","Toxicology","Diamondback moth","Avermectin","Pesticide","Lepidoptera genitalia","Botany","Agronomy"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Life in Land"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-10T19:05:34.461509Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}