{"doi":"10.1515/teb-2025-0009","title":"What are the optimal mind-body therapies for cancer-related pain? A network meta-analysis","abstract":"<jats:title>Abstract</jats:title>\n                  <jats:sec id=\"j_teb-2025-0009_abs_001\">\n                    <jats:title>Introduction</jats:title>\n                    <jats:p>Current international guidelines encourage cancer patients to engage in physical activity and recommend mind-body therapies (MBTs) as a method for treating cancer-related pain (CRP). However, the most effective MBTs for improving CRP in this population remain unknown. Therefore, this network meta-analysis (NMA) aimed to assess and rank the relative efficacy of different MBTs for CRP, and to conduct subgroup analyses according to different cancer types and stages of treatment.</jats:p>\n                  </jats:sec>\n                  <jats:sec id=\"j_teb-2025-0009_abs_002\">\n                    <jats:title>Content</jats:title>\n                    <jats:p>Eight electronic databases were searched for randomized controlled trials (RCTs) that compared different MBTs to improve pain in adults living with cancer. RCTs were evaluated using the Cochrane risk of bias tool. A random effects network meta-analysis was performed within a frequentist framework. Of the 4,916 articles retrieved and screened against the selection criteria. 36 studies with a total 2,387 participants were eligible to be included in the analysis. Qigong demonstrated significantly greater effects than Usual care (standardized mean difference [SMD] −0.85, 95 % confidence interval [CI] −1.46 to −0.24), Waitlist (SMD −0.93, −1.77 to −0.08), and Massage (SMD −1.71, −3.20 to −0.23), with the highest surface under the cumulative ranking value of 86.5 %, was ranked first. It was preceded by Conventional exercise (75.2 %), Taichi (74.9 %), with Massage having the lowest rank (7.2 %). In a subgroup analysis of breast cancer, Taichi (89.6 %), Conventional exercise (68.4 %), and Pilates (68.3 %) ranked as the top three.</jats:p>\n                  </jats:sec>\n                  <jats:sec id=\"j_teb-2025-0009_abs_003\">\n                    <jats:title>Summary and outlook</jats:title>\n                    <jats:p>This network meta-analysis indicates that Qigong and Tai Chi are among the most effective mind–body therapies (MBTs) for managing cancer-related pain and may serve as complementary adjuvant treatments for patients with cancer.</jats:p>\n                  </jats:sec>","journal":"Translational Exercise Biomedicine","year":2025,"id":621659,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":0,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1605471,"name":"Guangyuan Liang","orcid":null,"position":1,"is_corresponding":false},{"id":90188,"name":"Zhi Zou","orcid":null,"position":2,"is_corresponding":false},{"id":1605472,"name":"Siying Yu","orcid":null,"position":3,"is_corresponding":false},{"id":1605474,"name":"Youtian Lin","orcid":null,"position":4,"is_corresponding":false},{"id":1461670,"name":"Yafei Wang","orcid":"0000-0003-0309-6290","position":5,"is_corresponding":false},{"id":1605475,"name":"Yinhua Li","orcid":null,"position":6,"is_corresponding":false},{"id":1345324,"name":"Yuling Wang","orcid":"0000-0002-2079-3568","position":7,"is_corresponding":false},{"id":1367886,"name":"Xiaohui Hou","orcid":"0000-0002-8219-996X","position":8,"is_corresponding":false},{"id":1605470,"name":"Xiuyun He","orcid":"0009-0004-1190-7967","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"What are the optimal mind-body therapies for cancer-related pain? A network meta-analysis","abstract":"<jats:title>Abstract</jats:title>\n                  <jats:sec id=\"j_teb-2025-0009_abs_001\">\n                    <jats:title>Introduction</jats:title>\n                    <jats:p>Current international guidelines encourage cancer patients to engage in physical activity and recommend mind-body therapies (MBTs) as a method for treating cancer-related pain (CRP). However, the most effective MBTs for improving CRP in this population remain unknown. Therefore, this network meta-analysis (NMA) aimed to assess and rank the relative efficacy of different MBTs for CRP, and to conduct subgroup analyses according to different cancer types and stages of treatment.</jats:p>\n                  </jats:sec>\n                  <jats:sec id=\"j_teb-2025-0009_abs_002\">\n                    <jats:title>Content</jats:title>\n                    <jats:p>Eight electronic databases were searched for randomized controlled trials (RCTs) that compared different MBTs to improve pain in adults living with cancer. RCTs were evaluated using the Cochrane risk of bias tool. A random effects network meta-analysis was performed within a frequentist framework. Of the 4,916 articles retrieved and screened against the selection criteria. 36 studies with a total 2,387 participants were eligible to be included in the analysis. Qigong demonstrated significantly greater effects than Usual care (standardized mean difference [SMD] −0.85, 95 % confidence interval [CI] −1.46 to −0.24), Waitlist (SMD −0.93, −1.77 to −0.08), and Massage (SMD −1.71, −3.20 to −0.23), with the highest surface under the cumulative ranking value of 86.5 %, was ranked first. It was preceded by Conventional exercise (75.2 %), Taichi (74.9 %), with Massage having the lowest rank (7.2 %). In a subgroup analysis of breast cancer, Taichi (89.6 %), Conventional exercise (68.4 %), and Pilates (68.3 %) ranked as the top three.</jats:p>\n                  </jats:sec>\n                  <jats:sec id=\"j_teb-2025-0009_abs_003\">\n                    <jats:title>Summary and outlook</jats:title>\n                    <jats:p>This network meta-analysis indicates that Qigong and Tai Chi are among the most effective mind–body therapies (MBTs) for managing cancer-related pain and may serve as complementary adjuvant treatments for patients with cancer.</jats:p>\n                  </jats:sec>","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19767382","pmcid":null,"openalex_id":"https://openalex.org/W4411398812","authors":[],"funders":[{"funder_name":"the Research Foundation of Traditional Chinese Medicine Bureau of Guangdong Province","grant_id":"20231,067","title":null},{"funder_name":"the program of Guangdong Provincial Clinical Research Center for Rehabilitation Medicine","grant_id":"2023B110003","title":null},{"funder_name":"the Guangdong Hopson-Pearl River Education Development Foundation","grant_id":"No. H20190116202012724","title":null}],"total_grants":3,"fwci":0.0,"citation_percentile":0.15928095,"influential_citations":0,"citation_trend":[],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://www.degruyterbrill.com/document/doi/10.1515/teb-2025-0009/pdf","host_type":"journal"},{"url":"https://www.degruyterbrill.com/document/doi/10.1515/teb-2025-0009/pdf","host_type":"publisher"},{"url":"https://www.degruyterbrill.com/document/doi/10.1515/teb-2025-0009/xml","host_type":"publisher"},{"url":"https://doi.org/10.1515/teb-2025-0009","host_type":"journal"},{"url":"https://doaj.org/article/049fb228f324428881a75a0e4f48d050","host_type":"repository"}],"fields_of_study":["Cancer survivorship and care","Complementary and Alternative Medicine Studies","Acupuncture Treatment Research Studies"],"mesh_terms":[],"keywords":["Medicine","Meta-analysis","Massage","Physical therapy","Subgroup analysis","Cancer-related fatigue","Randomized controlled trial","Confidence interval","Breast cancer","Cancer","Acupuncture","Frequentist inference","Internal medicine","Alternative medicine","Statistics"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-03T15:29:01.732271Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}