{"doi":"10.1515/cdbme-2019-0144","title":"Biocompatibility of magnetic iron oxide nanoparticles for biomedical applications","abstract":"<jats:title>Abstract</jats:title>\n               <jats:p>Magnetic nanoparticles are highly promising for the usage in various biomedical applications including magnetic particle imaging (MPI), cancer hyperthermia treatment or as drug carriers. The present study aims at assessing in vitro biocompatibility of two commercially available magnetic iron oxide nanoparticle formulations: dextran-based magnetic nanoparticle synomag-D and bionized nanoferrite BNF-starch. Biological performance of both nanoparticle formulations were studied in human endothelial cells by analyzing cell viability and nanoparticle internalization in order to judge their suitability as theranostics.</jats:p>","journal":"Current Directions in Biomedical Engineering","year":2019,"id":677108,"datarank":0.26876392038420827,"base_score":1.791759469228055,"endowment":1.791759469228055,"self_citation_contribution":0.26876392038420827,"citation_network_contribution":0.0,"self_endowment_contribution":0.26876392038420827,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":5,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1769163,"name":"Anja Kowalski","orcid":null,"position":1,"is_corresponding":false},{"id":1769165,"name":"Knut Müller","orcid":null,"position":2,"is_corresponding":false},{"id":1769166,"name":"Henrik Teller","orcid":null,"position":3,"is_corresponding":false},{"id":1769168,"name":"Niels Grabow","orcid":null,"position":4,"is_corresponding":false},{"id":1769169,"name":"Swen Großmann","orcid":null,"position":5,"is_corresponding":false},{"id":1769170,"name":"Klaus-Peter Schmitz","orcid":null,"position":6,"is_corresponding":false},{"id":1769171,"name":"Stefan Siewert","orcid":null,"position":7,"is_corresponding":false},{"id":1769161,"name":"Claudia Matschegewski","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Biocompatibility of magnetic iron oxide nanoparticles for biomedical applications","abstract":"<jats:title>Abstract</jats:title>\n               <jats:p>Magnetic nanoparticles are highly promising for the usage in various biomedical applications including magnetic particle imaging (MPI), cancer hyperthermia treatment or as drug carriers. The present study aims at assessing in vitro biocompatibility of two commercially available magnetic iron oxide nanoparticle formulations: dextran-based magnetic nanoparticle synomag-D and bionized nanoferrite BNF-starch. Biological performance of both nanoparticle formulations were studied in human endothelial cells by analyzing cell viability and nanoparticle internalization in order to judge their suitability as theranostics.</jats:p>","is_dataset_classified":null,"base_score":1.791759469228055,"endowment":1.791759469228055,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"26207759","pmcid":null,"openalex_id":"https://openalex.org/W2974896378","authors":[],"funders":[],"total_grants":0,"fwci":0.2473,"citation_percentile":0.49309817,"influential_citations":0,"citation_trend":[{"year":2022,"count":3},{"year":2024,"count":1},{"year":2026,"count":1}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://www.degruyter.com/document/doi/10.1515/cdbme-2019-0144/pdf","host_type":"journal"},{"url":"https://www.degruyter.com/document/doi/10.1515/cdbme-2019-0144/pdf","host_type":"publisher"},{"url":"https://www.degruyter.com/view/journals/cdbme/5/1/article-p573.xml","host_type":"publisher"},{"url":"https://www.degruyter.com/document/doi/10.1515/cdbme-2019-0144/xml","host_type":"publisher"},{"url":"https://doi.org/10.1515/cdbme-2019-0144","host_type":"journal"},{"url":"https://doaj.org/article/67c5cd27e18d4dd19533eb7303730933","host_type":"repository"}],"fields_of_study":["Characterization and Applications of Magnetic Nanoparticles","Nanoparticle-Based Drug Delivery","Minerals Flotation and Separation Techniques"],"mesh_terms":[],"keywords":["Biocompatibility","Magnetic nanoparticles","Nanoparticle","Iron oxide nanoparticles","Nanotechnology","Materials science","Dextran","Magnetic hyperthermia","Iron oxide","Magnetic particle imaging","Biomedical engineering","Chemistry","Medicine","Chromatography"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-17T03:39:58.093050Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}