{"doi":"10.1515/cclm.1997.35.5.351","title":"Eosinophil Protein X Concentration Is Dependent on Eosinophil Concentration","abstract":null,"journal":"Clinical Chemistry and Laboratory Medicine","year":1997,"id":603522,"datarank":0.16479184330021646,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"self_citation_contribution":0.16479184330021646,"citation_network_contribution":0.0,"self_endowment_contribution":0.16479184330021646,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1548177,"name":"Piet C. M. Bartels","orcid":null,"position":1,"is_corresponding":false},{"id":1548176,"name":"Claudia J. Pronk-Admiraal","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Eosinophil Protein X Concentration Is Dependent on Eosinophil Concentration","abstract":"The relationship between the eosinophil concentration and the serum eosinophil protein X concentration was investigated in 80 subjects. Higher eosinophil counts resulted in obviously increased serum eosinophil protein X concentrations. However, the amount of eosinophil protein X released per eosinophil granulocyte is significantly higher in subjects with lower eosinophil counts. Atopic subjects (N = 19) show a significantly higher eosinophil concentration (p = 0.002) and eosinophil protein X concentration (p = 0.004) and a significantly lower eosinophil protein X/eosinophil ratio (p = 0.02), compared with non-atopic subjects (N = 61). However, there appears to be no difference between the concentration of eosinophil protein X in atopic and non-atopic subjects if the eosinophil concentration is taken into account. When using eosinophil protein X as an indicator of eosinophil activation, for instance in asthmatic subjects, the eosinophil count should also be considered for correct clinical interpretation of results.","is_dataset_classified":null,"base_score":1.0986122886681096,"endowment":1.0986122886681096,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"9189738","pmcid":null,"openalex_id":"https://openalex.org/W2096044583","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.13992417,"influential_citations":0,"citation_trend":[],"oa_status":"green","license":null,"oa_locations":[{"url":"https://edoc.hu-berlin.de/bitstreams/742868b0-919f-4030-a952-d9d108d941a2/download","host_type":"repository"},{"url":"https://edoc.hu-berlin.de/bitstreams/742868b0-919f-4030-a952-d9d108d941a2/download","host_type":"repository"},{"url":"https://www.degruyter.com/document/doi/10.1515/cclm.1997.35.5.351/pdf","host_type":"publisher"},{"url":"http://edoc.hu-berlin.de/18452/10186","host_type":"repository"},{"url":"https://doi.org/10.1515/cclm.1997.35.5.351","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/9189738","host_type":"repository"},{"url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.633.6660","host_type":""}],"fields_of_study":["Asthma and respiratory diseases","Eosinophilic Disorders and Syndromes","Eosinophilic Esophagitis","Adolescent","Adult","Blood Proteins","Eosinophil-Derived Neurotoxin","Eosinophils","Female","Humans","Hypersensitivity, Immediate","Immunoglobulin E","Leukocyte Count","Linear Models","Male","Middle Aged","Ribonucleases"],"mesh_terms":["Adolescent","Adult","Blood Proteins","Eosinophils","Female","Humans","Hypersensitivity, Immediate","Immunoglobulin E","Leukocyte Count","Male","Middle Aged","Ribonucleases","Linear Models","Eosinophil-Derived Neurotoxin"],"keywords":["Eosinophil","Eosinophil cationic protein","Major basic protein","Immunology","Medicine","Internal medicine","Asthma"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-07-29T22:09:14.172911Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}