{"doi":"10.1507/endocrj1954.35.511","title":"Proliferative Responese of Seminal Vesicle Cells to Androgen in Mice Castrated Neonatally and Pretreated with Estrogen or Androgen at Adulthood.","abstract":null,"journal":"Endocrinologia Japonica","year":1988,"id":613019,"datarank":0.20794415416798362,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"self_citation_contribution":0.20794415416798362,"citation_network_contribution":0.0,"self_endowment_contribution":0.20794415416798362,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1578925,"name":"TETSUMI YAMANE","orcid":null,"position":1,"is_corresponding":false},{"id":1578927,"name":"WEI LI","orcid":null,"position":2,"is_corresponding":false},{"id":1578929,"name":"NOBUYUKI TERADA","orcid":null,"position":3,"is_corresponding":false},{"id":1578930,"name":"YUKIHIKO KITAMURA","orcid":null,"position":4,"is_corresponding":false},{"id":1578932,"name":"KEISHI MATSUMOTO","orcid":null,"position":5,"is_corresponding":false},{"id":1578924,"name":"MASAHIRO AYATA","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Proliferative Responese of Seminal Vesicle Cells to Androgen in Mice Castrated Neonatally and Pretreated with Estrogen or Androgen at Adulthood.","abstract":"Seminal vesicle cells of neonatally castrated adult mice show poor response to androgen, compared to those of mice castrated at adulthood; effects of pretreatment with androgen or estrogen at adulthood on androgen-induced proliferation of the seminal vesicle cells were examined in neonatally castrated mice. Male mice castrated at day 0 after birth were pretreated with daily injections of testosterone propionate (TP, 100 micrograms/mouse), 17 beta-estradiol (E2, 5 micrograms/mouse) or vehicle for 20 days starting from day 60; daily TP injections (100 micrograms/mouse) for 30 days were started again from day 110 in all the pretreated mice to examine androgen-induced proliferation by incorporation of 5-[125I]iodo-2'-deoxyuridine into the whole seminal vesicles. Both TP and E2 pretreatments significantly increased the seminal vesicle weight found before TP treatment. However, androgen-induced proliferation of the seminal vesicle found in neonatally castrated mice (poor response; long duration with a low peak on day 3) was changed at least in part to that found in mice castrated at adulthood (good response; short duration with a high peak on day 3) only following the TP pretreatment but not at all following the E2 pretreatment. The E2 pretreatment induced poor androgen-induced proliferation with a low peak on day 7.","is_dataset_classified":null,"base_score":1.3862943611198906,"endowment":1.3862943611198906,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"3197662","pmcid":null,"openalex_id":"https://openalex.org/W2019264195","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.08747795,"influential_citations":0,"citation_trend":[{"year":2012,"count":1},{"year":2014,"count":1},{"year":2024,"count":1}],"oa_status":"bronze","license":null,"oa_locations":[{"url":"https://www.jstage.jst.go.jp/article/endocrj1954/35/3/35_3_511/_pdf","host_type":"journal"},{"url":"https://www.jstage.jst.go.jp/article/endocrj1954/35/3/35_3_511/_pdf","host_type":"publisher"},{"url":"http://www.jstage.jst.go.jp/article/endocrj1954/35/3/35_3_511/_pdf","host_type":"publisher"},{"url":"https://doi.org/10.1507/endocrj1954.35.511","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/3197662","host_type":"repository"}],"fields_of_study":["Hormonal and reproductive studies","Xenotransplantation and immune response","Sperm and Testicular Function"],"mesh_terms":["Age Factors","Androgens","Animals","Cell Division","Estradiol","Estrogens","Idoxuridine","Male","Mice, Inbred Strains","Orchiectomy","Organ Size","Seminal Vesicles","Testis","Testosterone","Mice"],"keywords":["Testosterone propionate","Endocrinology","Internal medicine","Androgen","Seminal vesicle","Castration","Estrogen","Testosterone (patch)","Biology","Prostate","Medicine","Hormone"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-02T06:10:48.605480Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}