{"doi":"10.14503/thij-21-7680","title":"Gadolinium-Based Contrast Agents: Updates and Answers to Typical Questions Regarding Gadolinium Use","abstract":"<jats:p>Gadolinium-based contrast agents have expanded the diagnostic usefulness and capability of magnetic resonance imaging. Despite their highly favorable safety profile, these agents have been associated with nephrogenic systemic fibrosis in a small number of patients who have advanced kidney disease. Recently, trace amounts of gadolinium deposition in the brain and other organs have been reported after contrast exposure, even in patients with normal renal function. In this review, we provide a brief overview of recent updates and discuss typical clinical situations related to the use of gadolinium-based contrast agents.</jats:p>","journal":"Texas Heart Institute Journal","year":2022,"id":686061,"datarank":0.5641800173540344,"base_score":3.7612001156935624,"endowment":3.7612001156935624,"self_citation_contribution":0.5641800173540344,"citation_network_contribution":0.0,"self_endowment_contribution":0.5641800173540344,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":42,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":88901,"name":"James M. Wilson","orcid":"0000-0002-9630-3131","position":1,"is_corresponding":false},{"id":1792418,"name":"Ourania A. Preventza","orcid":null,"position":2,"is_corresponding":false},{"id":845667,"name":"Raja Muthupillai","orcid":"0000-0001-5041-2562","position":3,"is_corresponding":false},{"id":1792417,"name":"Benjamin Y.C. Cheong","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Gadolinium-Based Contrast Agents: Updates and Answers to Typical Questions Regarding Gadolinium Use","abstract":"<jats:p>Gadolinium-based contrast agents have expanded the diagnostic usefulness and capability of magnetic resonance imaging. Despite their highly favorable safety profile, these agents have been associated with nephrogenic systemic fibrosis in a small number of patients who have advanced kidney disease. Recently, trace amounts of gadolinium deposition in the brain and other organs have been reported after contrast exposure, even in patients with normal renal function. In this review, we provide a brief overview of recent updates and discuss typical clinical situations related to the use of gadolinium-based contrast agents.</jats:p>","is_dataset_classified":null,"base_score":3.7612001156935624,"endowment":3.7612001156935624,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"35612906","pmcid":"PMC9242635","openalex_id":"https://openalex.org/W4281482713","authors":[],"funders":[],"total_grants":0,"fwci":2.7394,"citation_percentile":0.91617511,"influential_citations":0,"citation_trend":[{"year":2022,"count":2},{"year":2023,"count":9},{"year":2024,"count":19},{"year":2025,"count":10},{"year":2026,"count":2}],"oa_status":"gold","license":null,"oa_locations":[{"url":"https://doi.org/10.14503/thij-21-7680","host_type":"journal"},{"url":"https://doi.org/10.14503/thij-21-7680","host_type":"publisher"},{"url":"https://thij.kglmeridian.com/view/journals/thij/49/3/article-e217680.xml","host_type":"publisher"},{"url":"https://meridian.allenpress.com/thij/article-pdf/doi/10.14503/THIJ-21-7680/3063932/i1526-6702-49-3-e217680.pdf","host_type":"publisher"},{"url":"https://thij.kglmeridian.com/downloadpdf/journals/thij/49/3/article-e217680.xml","host_type":"publisher"},{"url":"https://pubmed.ncbi.nlm.nih.gov/35612906","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9242635","host_type":"repository"}],"fields_of_study":["Lanthanide and Transition Metal Complexes","Advanced MRI Techniques and Applications","MRI in cancer diagnosis","Contrast Media","Gadolinium","Humans","Magnetic Resonance Imaging","Nephrogenic Fibrosing Dermopathy","Renal Insufficiency"],"mesh_terms":["Contrast Media","Gadolinium","Humans","Magnetic Resonance Imaging","Renal Insufficiency","Nephrogenic Fibrosing Dermopathy"],"keywords":["Nephrogenic systemic fibrosis","Gadolinium","Medicine","Contrast (vision)","Magnetic resonance imaging","Radiology","Computer science","Artificial intelligence","risk factors","Practice Guidelines As Topic","Renal Dialysis","Kidney Failure, Chronic/complications","Image Enhancement/methods","Kidney/diagnostic Imaging","Acute Kidney Injury/complications","Gadolinium/administration & Dosage/adverse Effects","Nephrogenic Fibrosing Dermopathy/chemically Induced/prevention & Control"],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-18T18:26:44.735784Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}