{"doi":"10.14341/2071-8713-5129","title":"Clinical case: multiple endocrine neoplasia type 1 (MEN 1)","abstract":"<jats:p>Multiple endocrine neoplasia syndrome type 1 (MEN1, Wermer syndrome) – group o а heterogeneous inherited deseases, caused by hyperlasia or neoplasia of several endocrine glands. The phenotype of MEN1 is broad, and over 20 different combinations of endocrine and non-endocrine metabolic manifestations have been described. This case demonstrates multiple formations of endocrine organs, starting non-classical with macroprolactonoma resistant to dopamine agonists therapy, other endocrine disorders developed gradually eventually: hyperparathyreoidism and hypoglycemia caused by pancreas lesions, produced proinsulin in high levels.</jats:p>","journal":"Obesity and metabolism","year":2012,"id":42998,"datarank":0.1349812930564104,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.031009215972418604,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.031009215972418604,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":1,"citers_with_citation_signal":1,"citers_with_endowment":1,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":204967,"name":"L K Dzeranova","orcid":null,"position":1,"is_corresponding":false},{"id":204968,"name":"E A Pigarova","orcid":null,"position":2,"is_corresponding":false},{"id":204969,"name":"L Ya Rozhinskaya","orcid":null,"position":3,"is_corresponding":false},{"id":204970,"name":"A V Kochatkov","orcid":null,"position":4,"is_corresponding":false},{"id":204966,"name":"A K Lipatenkova","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"18998881","pmcid":null,"openalex_id":"https://openalex.org/W1972397490","authors":[],"funders":[],"total_grants":0,"fwci":0.0,"citation_percentile":0.07907026,"influential_citations":0,"citation_trend":[{"year":2023,"count":1}],"oa_status":"gold","license":"cc-by-nc-nd","oa_locations":[{"url":"https://www.omet-endojournals.ru/jour/article/download/5129/2947","host_type":"journal"},{"url":"https://www.omet-endojournals.ru/jour/article/download/5129/2947","host_type":"GOLD"},{"url":"https://www.omet-endojournals.ru/jour/article/download/5129/2947","host_type":"publisher"},{"url":"https://omet-endojournals.ru/omet/article/viewFile/5129/2947","host_type":"publisher"},{"url":"https://doi.org/10.14341/2071-8713-5129","host_type":"journal"},{"url":"https://doaj.org/article/6a39601c34e147fdb5657d9bf386f60c","host_type":"repository"}],"fields_of_study":["Neuroendocrine Tumor Research Advances","Neuroblastoma Research and Treatments","Cancer, Hypoxia, and Metabolism","Biology","Medicine"],"mesh_terms":[],"keywords":["Endocrine system","Multiple endocrine neoplasia","MEN1","Pancreas","Endocrinology","Medicine","Internal medicine","Endocrine gland","Biology","Hormone","Genetics","Gene"],"sdg_mappings":[{"sdg_number":0,"sdg_label":"Good health and well-being"}],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-14T12:26:29.075963Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}