{"doi":"10.14238/pi44.2.2004.61-5","title":"Correlation between leukocyte aggregation score of cerebrospinal fluid and bacterial meningitis in children","abstract":"<jats:p>Background Bacterial meningitis is one of life-threatening dis-eases and carries a risk of sequelae in affected children. In termsof cost and rapid differentiation between bacterial and non-bacte-rial meningitis, several tests have been proposed.Objective This study aimed to determine the use of leukocyteaggregation score (LAS) of cerebrospinal fluid (CSF) in diagnos-ing bacterial meningitis.Methods A prospective analytic study was done from October 2001to July 2002 in the Department of Child Health, Medical School,Sam Ratulangi University/ Manado General Hospital. Children pre-senting with symptoms of meningitis, aged between 28 days and13 years were enrolled. LAS was counted in percentage. Regres-sion analysis was used to determine the correlation between LASand diagnosis of bacterial meningitis.Results CSF examinations were done on 35 meningitis patients.Three patients were excluded. The remaining 32 patients com-prised of 11 with bacterial meningitis and the other 21 with non-bacterial meningitis. The mean of LAS in bacterial meningitis wassignificantly higher than that of non-bacterial meningitis (p&lt;0.001).The cut off value of LAS to diagnose bacterial meningitis was12.35%.Conclusion LAS may be used as a fast and simple alternativediagnostic tool to confirm the diagnosis of bacterial meningitis</jats:p>","journal":"Paediatrica Indonesiana","year":2016,"id":618060,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1594200,"name":"Nurhayati Masloman","orcid":null,"position":1,"is_corresponding":false},{"id":1594199,"name":"Meitha PE Togas","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Correlation between leukocyte aggregation score of cerebrospinal fluid and bacterial meningitis in children","abstract":"<jats:p>Background Bacterial meningitis is one of life-threatening dis-eases and carries a risk of sequelae in affected children. In termsof cost and rapid differentiation between bacterial and non-bacte-rial meningitis, several tests have been proposed.Objective This study aimed to determine the use of leukocyteaggregation score (LAS) of cerebrospinal fluid (CSF) in diagnos-ing bacterial meningitis.Methods A prospective analytic study was done from October 2001to July 2002 in the Department of Child Health, Medical School,Sam Ratulangi University/ Manado General Hospital. Children pre-senting with symptoms of meningitis, aged between 28 days and13 years were enrolled. LAS was counted in percentage. Regres-sion analysis was used to determine the correlation between LASand diagnosis of bacterial meningitis.Results CSF examinations were done on 35 meningitis patients.Three patients were excluded. The remaining 32 patients com-prised of 11 with bacterial meningitis and the other 21 with non-bacterial meningitis. The mean of LAS in bacterial meningitis wassignificantly higher than that of non-bacterial meningitis (p&lt;0.001).The cut off value of LAS to diagnose bacterial meningitis was12.35%.Conclusion LAS may be used as a fast and simple alternativediagnostic tool to confirm the diagnosis of bacterial meningitis</jats:p>","is_dataset_classified":null,"base_score":0.0,"endowment":0.0,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"19910364","pmcid":null,"openalex_id":null,"authors":[],"funders":[],"total_grants":0,"fwci":null,"citation_percentile":null,"influential_citations":0,"citation_trend":[],"oa_status":"gold","license":"cc-by-nc-sa","oa_locations":[{"url":"https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/download/738/590","host_type":"publisher"},{"url":"https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/viewFile/738/590","host_type":"publisher"},{"url":"https://doaj.org/article/1b24bfeb4f2241509f7e23a9213247f9","host_type":"repository"}],"fields_of_study":[],"mesh_terms":[],"keywords":[],"sdg_mappings":[],"linked_datasets":[],"clinical_trials":[],"software_tools":[],"database_accessions":[],"source":"live","citation_network_status":"fetched"},"created_at":"2026-08-03T03:20:03.242949Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}