{"doi":"10.1375/1832427054936763","title":"Verification of Self-Report of Zygosity Determined via DNA Testing in a Subset of the NAS-NRC Twin Registry 40 Years Later","abstract":null,"journal":"Twin Research and Human Genetics","year":2005,"id":623963,"datarank":3.6990355569769453,"base_score":4.23410650459726,"endowment":4.23410650459726,"self_citation_contribution":0.635115975689589,"citation_network_contribution":3.0639195812873563,"self_endowment_contribution":0.635115975689589,"citer_contribution":3.0639195812873563,"corpus_percentile":null,"corpus_rank":null,"citation_count":68,"citer_count":56,"citers_with_citation_signal":53,"citers_with_endowment":53,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":245214,"name":"Brenda L. Plassman","orcid":"0000-0003-2867-7198","position":1,"is_corresponding":false},{"id":246443,"name":"Caroline M. Tanner","orcid":"0000-0002-3775-5082","position":2,"is_corresponding":false},{"id":230703,"name":"Danielle M. Dick","orcid":"0000-0002-1636-893X","position":3,"is_corresponding":false},{"id":1612858,"name":"Shannon A. Rinehart","orcid":null,"position":4,"is_corresponding":false},{"id":270322,"name":"William C. 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The sample was supplemented from two other studies using NAS-NRC twins where one or both co-twins were suspected to have Alzheimer disease or another dementia, or Parkinson's disease. Overall 578 twin pairs with DNA were analyzed. Zygosity assignment for 96.8% (519/536) was confirmed via questionnaire. Among 42 pairs whose questionnaire responses were inconclusive for assigning zygosity, 50% were found to be monozygous (MZ) and 50% were dizygous (DZ). There was some evidence for greater misclassification of presumed DZ pairs in the healthy ageing study where participation favored pairs who were similar in having a favorable health history and willingness to volunteer without any element of perceived risk for a specific disease influencing participation.","is_dataset_classified":null,"base_score":4.23410650459726,"endowment":4.23410650459726,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"16176721","pmcid":"PMC1262657","openalex_id":"https://openalex.org/W2008440492","authors":[],"funders":[{"funder_name":"NIA NIH HHS","grant_id":"AG18736","title":null},{"funder_name":"NINDS NIH HHS","grant_id":"R01 NS040467","title":null},{"funder_name":"NIA NIH HHS","grant_id":"R01 AG008549","title":null},{"funder_name":"NIA NIH HHS","grant_id":"AG08549","title":null},{"funder_name":"NINDS NIH HHS","grant_id":"NS31321","title":null},{"funder_name":"NINDS NIH HHS","grant_id":"NS40467","title":null},{"funder_name":"NIA NIH HHS","grant_id":"R01 AG018736","title":null},{"funder_name":"National Institutes of Health","grant_id":"3R01NS040467-02S1","title":"TWINS AND RISK OF PD: A CLINICAL AND IMAGING STUDY"},{"funder_name":"National Institutes of Health","grant_id":"1U10NS031321-01","title":"TWIN STUDIES IN PARKINSONS DISEASE"}],"total_grants":9,"fwci":1.958,"citation_percentile":0.85302615,"influential_citations":0,"citation_trend":[{"year":2012,"count":2},{"year":2013,"count":6},{"year":2014,"count":4},{"year":2015,"count":2},{"year":2016,"count":2},{"year":2017,"count":2},{"year":2018,"count":3},{"year":2019,"count":5},{"year":2020,"count":5},{"year":2021,"count":3},{"year":2022,"count":2},{"year":2023,"count":2},{"year":2024,"count":1}],"oa_status":"green","license":"Cambridge Core User Agreement","oa_locations":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1262657","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1262657","host_type":"repository"},{"url":"https://doi.org/10.1375/1832427054936763","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/16176721","host_type":"repository"},{"url":"https://hdl.handle.net/1805/55537","host_type":"repository"},{"url":"https://doi.org/10.1375/twin.8.4.362","host_type":""},{"url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/4B6901C381029CF84F418D62377D4925/S1832427400005521a.pdf/div-class-title-verification-of-self-report-of-zygosity-determined-via-dna-testing-in-a-subset-of-the-nas-nrc-twin-registry-40-years-later-div.pdf","host_type":""},{"url":"https://europepmc.org/articles/pmc1262657?pdf=render","host_type":""},{"url":"https://dx.doi.org/10.1375/1832427054936763","host_type":""}],"fields_of_study":["BRCA gene mutations in cancer","Cognitive Abilities and Testing","Genetic Associations and Epidemiology","0301 basic medicine","0303 health sciences","03 medical and health sciences","Adult","Aged","DNA","Genotype","Humans","Surveys and Questionnaires","Twins, Dizygotic","Twins, Monozygotic"],"mesh_terms":["Adult","Aged","DNA","Genotype","Humans","Surveys and Questionnaires","Twins, Dizygotic","Twins, Monozygotic"],"keywords":["Zygosity","Twin study","Medicine","Psychology","Genetics","Biology","Heritability","Adult","Genotype","DNA","Twins, Monozygotic","Surveys and Questionnaires","Twins, Dizygotic","Humans","Aged"],"sdg_mappings":[{"sdg_number":3,"sdg_label":"3. 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