{"doi":"10.1371/journal.pone.0305165","title":"Assessing the impact of jail-initiated medication for opioid use disorder: A multisite analysis of the SOMATICS collaborative","abstract":"The objective of this study was to estimate the associations of jail-initiated medication for opioid use disorder (MOUD) and patient navigation (PN) with opioid use disorder (OUD) at 6 months post-release. Three randomized trials (combined N = 330) were combined to assess whether MOUD (extended-release naltrexone or interim methadone) initiated prior to release from jail with or without PN would reduce the likelihood of a DSM-5 diagnosis of OUD 6 months post-release relative to enhanced treatment-as-usual (ETAU). Across the three studies, assignment to MOUD compared to ETAU was not associated with an OUD diagnosis at 6 months post-release (69% vs. 75%, respectively, OR = 0.67, 95% CI: 0.42 to 1.20). Similarly, PN compared to MOUD without PN was not associated with an OUD diagnosis (63% vs 77%, respectively, OR = 0.61, 95% CI: 0.27 to 1.53). Results underscore the need to further optimize the effectiveness of MOUD for patients initiating treatment in jail, beginning with an emphasis on post-release treatment adherence.","journal":"PLoS ONE","year":2024,"id":473525,"datarank":0.10397207708399181,"base_score":0.6931471805599453,"endowment":0.6931471805599453,"self_citation_contribution":0.10397207708399181,"citation_network_contribution":0.0,"self_endowment_contribution":0.10397207708399181,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":1,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9651,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":381424,"name":"Keith Goldfeld","orcid":"0000-0002-0292-8780","position":1,"is_corresponding":false},{"id":315656,"name":"Robert P. Schwartz","orcid":"0000-0002-4707-5726","position":2,"is_corresponding":false},{"id":738378,"name":"Ryan McDonald","orcid":"0000-0001-5346-5336","position":3,"is_corresponding":false},{"id":1064663,"name":"Yifan Xu","orcid":"0000-0002-8999-2565","position":4,"is_corresponding":false},{"id":427549,"name":"Redonna Chandler","orcid":null,"position":5,"is_corresponding":false},{"id":395933,"name":"Kevin A. Hallgren","orcid":"0000-0001-8386-3984","position":6,"is_corresponding":false},{"id":419713,"name":"Sharon M. Kelly","orcid":"0000-0002-3516-1387","position":7,"is_corresponding":false},{"id":448429,"name":"Shannon Mitchell","orcid":null,"position":8,"is_corresponding":false},{"id":419715,"name":"Anjalee Sharma","orcid":"0000-0001-8872-4756","position":9,"is_corresponding":false},{"id":938286,"name":"David Farabee","orcid":"0000-0002-0398-205X","position":10,"is_corresponding":false},{"id":453116,"name":"Joshua D. Lee","orcid":"0000-0003-3161-2950","position":0,"is_corresponding":true}],"reference_count":21,"raw_metadata":{"citation_network_status":"fetched"},"created_at":"2026-07-19T02:06:04.967429Z","pmid":"38885220","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}