{"doi":"10.1371/journal.pone.0302077","title":"Preferences and uptake of home-based HIV self-testing for maternal retesting in Kenya","abstract":"OBJECTIVE: To compare preferences, uptake, and cofactors for unassisted home-based oral self-testing (HB-HIVST) versus clinic-based rapid diagnostic blood tests (CB-RDT) for maternal HIV retesting. DESIGN: Prospective cohort. METHODS: Between November 2017 and June 2019, HIV-negative pregnant Kenyan women receiving antenatal care were enrolled and given a choice to retest with HB-HIVST or CB-RDT. Women were asked to retest between 36 weeks gestation and 1-week post-delivery if the last HIV test was <24 weeks gestation or at 6 weeks postpartum if ≥24 weeks gestation, and self-report on retesting at a 14-week postpartum. RESULTS: Overall, 994 women enrolled and 33% (n = 330) selected HB-HIVST. HB-HIVST was selected because it was private (n = 224, 68%), convenient (n = 211, 63%), and offered flexibility in the timing of retesting (n = 207, 63%), whereas CB-RDT was selected due to the trust of providers to administer the test (n = 510, 77%) and convenience of clinic testing (n = 423, 64%). Among 905 women who reported retesting at follow-up, 135 (15%) used HB-HIVST. Most (n = 595, 94%) who selected CB-RDT retested with this strategy, compared to 39% (n = 120) who selected HB-HIVST retesting with HB-HIVST. HB-HIVST retesting was more common among women with higher household income and those who may have been unable to test during pregnancy (both retested postpartum and delivered <37 weeks gestation) and less common among women who were depressed. Most women said they would retest in the future using the test selected at enrollment (99% [n = 133] HB-HIVST; 93% [n = 715] CB-RDT-RDT). CONCLUSIONS: While most women preferred CB-RDT for maternal retesting, HB-HIVST was acceptable and feasible and could be used to expand HIV retesting options.","journal":"PLoS ONE","year":2024,"id":471632,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9525,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":662965,"name":"Wenwen Jiang","orcid":"0000-0002-0579-9443","position":1,"is_corresponding":false},{"id":1306815,"name":"Peninah Kitao","orcid":null,"position":2,"is_corresponding":false},{"id":692172,"name":"Shiza Farid","orcid":"0000-0002-8490-1193","position":3,"is_corresponding":false},{"id":407491,"name":"Barbra A. Richardson","orcid":"0000-0001-9564-1828","position":4,"is_corresponding":false},{"id":289071,"name":"David A. Katz","orcid":"0000-0002-7786-0194","position":5,"is_corresponding":false},{"id":299047,"name":"Anjuli D. Wagner","orcid":"0000-0002-5851-1220","position":6,"is_corresponding":false},{"id":315409,"name":"Cheryl Johnson","orcid":"0000-0001-5499-5523","position":7,"is_corresponding":false},{"id":445175,"name":"Daniel Matemo","orcid":"0000-0002-7209-1648","position":8,"is_corresponding":false},{"id":1306816,"name":"Grace-John Stewart","orcid":null,"position":9,"is_corresponding":false},{"id":299054,"name":"John Kinuthia","orcid":"0000-0001-6571-8927","position":10,"is_corresponding":false},{"id":315410,"name":"Alison L. Drake","orcid":"0000-0002-4178-7706","position":0,"is_corresponding":true}],"reference_count":33,"raw_metadata":null,"created_at":"2026-07-19T02:05:48.788780Z","pmid":"39137189","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}