{"doi":"10.1371/journal.pone.0267705","title":"Biological sample donation and informed consent for neurobiobanking: Evidence from a community survey in Ghana and Nigeria","abstract":"INTRODUCTION: Genomic research and neurobiobanking are expanding globally. Empirical evidence on the level of awareness and willingness to donate/share biological samples towards the expansion of neurobiobanking in sub-Saharan Africa is lacking. AIMS: To ascertain the awareness, perspectives and predictors regarding biological sample donation, sharing and informed consent preferences among community members in Ghana and Nigeria. METHODS: A questionnaire cross-sectional survey was conducted among randomly selected community members from seven communities in Ghana and Nigeria. RESULTS: Of the 1015 respondents with mean age 39.3 years (SD 19.5), about a third had heard of blood donation (37.2%, M: 42.4%, F: 32.0%, p = 0.001) and a quarter were aware of blood sample storage for research (24.5%; M: 29.7%, F: 19.4%, p = 0.151). Two out of ten were willing to donate brain after death (18.8%, M: 22.6%, F: 15.0%, p<0.001). Main reasons for unwillingness to donate brain were; to go back to God complete (46.6%) and lack of knowledge related to brain donation (32.7%). Only a third of the participants were aware of informed consent (31.7%; M: 35.9%, F: 27.5%, p<0.001). Predictors of positive attitude towards biobanking and informed consent were being married, tertiary level education, student status, and belonging to select ethnic groups. CONCLUSION: There is a greater need for research attention in the area of brain banking and informed consent. Improved context-sensitive public education on neurobiobanking and informed consent, in line with the sociocultural diversities, is recommended within the African sub region.","journal":"PLoS ONE","year":2022,"id":261191,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":15,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9687,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":503158,"name":"Oyedunni Arulogun","orcid":"0000-0002-2173-4682","position":1,"is_corresponding":false},{"id":503144,"name":"Joshua Akinyemi","orcid":"0000-0002-0675-2110","position":2,"is_corresponding":false},{"id":363933,"name":"Michelle Nichols","orcid":"0000-0002-2078-9649","position":3,"is_corresponding":false},{"id":503149,"name":"Benedict Calys‐Tagoe","orcid":"0000-0002-6133-240X","position":4,"is_corresponding":false},{"id":503145,"name":"Babatunde Raphael Ojebuyi","orcid":"0000-0002-1383-7630","position":5,"is_corresponding":false},{"id":265990,"name":"Carolyn Jenkins","orcid":"0000-0001-5506-7657","position":6,"is_corresponding":false},{"id":503143,"name":"Reginald Obiako","orcid":"0000-0003-1769-8110","position":7,"is_corresponding":false},{"id":503141,"name":"Albert Akpalu","orcid":"0000-0002-4802-9852","position":8,"is_corresponding":false},{"id":369186,"name":"Fred Stephen Sarfo","orcid":"0000-0001-7274-5093","position":9,"is_corresponding":false},{"id":446878,"name":"Kolawole Wahab","orcid":"0000-0002-2914-1953","position":10,"is_corresponding":false},{"id":916022,"name":"Adeniyi Sunday","orcid":null,"position":11,"is_corresponding":false},{"id":503142,"name":"Lukman Owolabi","orcid":"0000-0001-9509-1440","position":12,"is_corresponding":false},{"id":503146,"name":"Muyiwa Adigun","orcid":"0000-0001-9898-6178","position":13,"is_corresponding":false},{"id":915441,"name":"Ibukun Afolami","orcid":"0000-0003-3790-3214","position":14,"is_corresponding":false},{"id":503154,"name":"Olorunyomi Olorunsogbon","orcid":"0000-0002-2373-1987","position":15,"is_corresponding":false},{"id":503150,"name":"Mayowa Ogunronbi","orcid":"0000-0003-4104-2728","position":16,"is_corresponding":false},{"id":435976,"name":"Ezinne Sylvia Melikam","orcid":"0000-0002-8156-4195","position":17,"is_corresponding":false},{"id":503152,"name":"Ruth Laryea","orcid":"0000-0002-7963-6145","position":18,"is_corresponding":false},{"id":761791,"name":"Shadrack Osei Asibey","orcid":"0000-0002-4258-6885","position":19,"is_corresponding":false},{"id":503999,"name":"Wisdom Oguike","orcid":null,"position":20,"is_corresponding":false},{"id":916023,"name":"Lois Melikam","orcid":null,"position":21,"is_corresponding":false},{"id":915442,"name":"Abdullateef Sule","orcid":"0000-0002-9622-6666","position":22,"is_corresponding":false},{"id":503148,"name":"Musibau A. 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