{"doi":"10.1371/journal.pntd.0012626","title":"Temperature and photoperiod differentially impact maternal phenotypes in diapause egg-laying Aedes albopictus mosquitoes","abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background</jats:title>\n<jats:p><jats:italic>Aedes albopictus</jats:italic> (Skuse 1894) mosquitoes can transmit deadly arboviruses and are globally invasive due to their ability to survive in both tropical and temperate climates. Although adults cannot survive harsh winters, females are capable of anticipating seasonal change and producing overwintering diapause (DP) eggs that remain in a state of arrested development over the winter and hatch when favorable conditions return in the spring. While low temperatures can facilitate DP entry under short photoperiods, temperature signals alone are not sufficient to induce DP.</jats:p>\n</jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methodology/Principal findings</jats:title>\n<jats:p>To identify maternal phenotypes predictive of DP egg production in laboratory conditions, we characterized aspects of maternal physiology and behavior to identify those that correlate with DP egg production and changes in photoperiod, versus changes in temperature. Neither changes in temperature nor photoperiod impacted protein preference, blood meal consumption, or total number of eggs produced per female. Egg retention and oviposition timing were influenced by temperature, independent of DP egg production. However, females housed under short photoperiod conditions showed increased starvation resistance, despite showing similar levels of locomotor activity and internal stores of triacylglycerols, glucose, glycogen, and trehalose compared to females housed in long photoperiods.</jats:p>\n</jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Conclusions/Significance</jats:title>\n<jats:p>These results suggest that temperature and photoperiod differentially affect maternal phenotypes and identify starvation resistance as a maternal phenotype that is influenced by photoperiod and correlates with DP egg status.</jats:p>\n</jats:sec>","journal":"PLOS Neglected Tropical Diseases","year":2024,"id":625710,"datarank":0.32958368660043297,"base_score":2.1972245773362196,"endowment":2.1972245773362196,"self_citation_contribution":0.32958368660043297,"citation_network_contribution":0.0,"self_endowment_contribution":0.32958368660043297,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":8,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":null,"is_data_producer":false,"deposit_databanks":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1618360,"name":"Anthony S. Lee","orcid":"0009-0006-5109-4440","position":1,"is_corresponding":false},{"id":749883,"name":"Helen V. Kogan","orcid":"0000-0002-6149-6674","position":2,"is_corresponding":false},{"id":1367628,"name":"Linhan Dong","orcid":"0009-0002-6668-2326","position":3,"is_corresponding":false},{"id":376579,"name":"Laura B. Duvall","orcid":"0000-0002-1821-6809","position":4,"is_corresponding":false},{"id":750167,"name":"In Hae Lee","orcid":"0000-0001-8210-8661","position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"resolved":true,"title":"Temperature and photoperiod differentially impact maternal phenotypes in diapause egg-laying Aedes albopictus mosquitoes","abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background</jats:title>\n<jats:p><jats:italic>Aedes albopictus</jats:italic> (Skuse 1894) mosquitoes can transmit deadly arboviruses and are globally invasive due to their ability to survive in both tropical and temperate climates. Although adults cannot survive harsh winters, females are capable of anticipating seasonal change and producing overwintering diapause (DP) eggs that remain in a state of arrested development over the winter and hatch when favorable conditions return in the spring. While low temperatures can facilitate DP entry under short photoperiods, temperature signals alone are not sufficient to induce DP.</jats:p>\n</jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methodology/Principal findings</jats:title>\n<jats:p>To identify maternal phenotypes predictive of DP egg production in laboratory conditions, we characterized aspects of maternal physiology and behavior to identify those that correlate with DP egg production and changes in photoperiod, versus changes in temperature. Neither changes in temperature nor photoperiod impacted protein preference, blood meal consumption, or total number of eggs produced per female. Egg retention and oviposition timing were influenced by temperature, independent of DP egg production. However, females housed under short photoperiod conditions showed increased starvation resistance, despite showing similar levels of locomotor activity and internal stores of triacylglycerols, glucose, glycogen, and trehalose compared to females housed in long photoperiods.</jats:p>\n</jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Conclusions/Significance</jats:title>\n<jats:p>These results suggest that temperature and photoperiod differentially affect maternal phenotypes and identify starvation resistance as a maternal phenotype that is influenced by photoperiod and correlates with DP egg status.</jats:p>\n</jats:sec>","is_dataset_classified":null,"base_score":2.0794415416798357,"endowment":2.0794415416798357,"datacite_reuse_total":0,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"39480906","pmcid":"PMC11556710","openalex_id":"https://openalex.org/W4403936430","authors":[],"funders":[{"funder_name":"National Institute of General Medical Sciences","grant_id":"R35 GM137888","title":null},{"funder_name":"Arnold and Mabel Beckman Foundation","grant_id":"Beckman Young Investigator Award","title":null},{"funder_name":"Pew Charitable Trusts","grant_id":"Pew Biomedical Scholar Award","title":null},{"funder_name":"Esther A. and Joseph Klingenstein Fund","grant_id":"Klingenstein-Simons Fellowship Award in Neuroscience","title":null},{"funder_name":"National Institutes of Health","grant_id":"5R35GM137888-02","title":"Peptide regulation of blood-feeding and mating physiology in mosquitoes"}],"total_grants":5,"fwci":2.8714,"citation_percentile":0.91379215,"influential_citations":0,"citation_trend":[{"year":2025,"count":3},{"year":2026,"count":4}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0012626&type=printable","host_type":"journal"},{"url":"https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0012626&type=printable","host_type":"publisher"},{"url":"https://dx.plos.org/10.1371/journal.pntd.0012626","host_type":"publisher"},{"url":"https://doi.org/10.1371/journal.pntd.0012626","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/39480906","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11556710","host_type":"repository"},{"url":"https://doaj.org/article/9b5b9e84c01e45158faaccde1cacedc1","host_type":"repository"},{"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11556710/pdf/pntd.0012626.pdf","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC11556710","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC11556710?pdf=render","host_type":"Europe_PMC"},{"url":"https://doi.org/10.1101/2024.04.19.590231","host_type":""},{"url":"http://dx.doi.org/10.1371/journal.pntd.0012626","host_type":""}],"fields_of_study":["Mosquito-borne diseases and control","Malaria Research and Control","Neurobiology and Insect Physiology Research","0106 biological sciences","01 natural sciences","Animals","Photoperiod","Aedes","Female","Temperature","Oviposition","Phenotype","Diapause, Insect","Seasons","Diapause","Ovum","Aedes albopictus"],"mesh_terms":["Diapause","Aedes","Animals","Female","Oviposition","Ovum","Phenotype","Seasons","Temperature","Photoperiod","Diapause, Insect"],"keywords":["Biology","Diapause","photoperiodism","Overwintering","Aedes albopictus","Blood meal","Phenotypic plasticity","Zoology","Glycogen","Reproduction","Animal science","Ecology","Endocrinology","Aedes aegypti","Botany","Larva","Photoperiod","Oviposition","RC955-962","Temperature","Diapause, Insect","Phenotype","Aedes","Arctic medicine. 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