{"doi":"10.1371/journal.pntd.0010794","title":"SARS-CoV-2 seroprevalence on the north coast of Peru: A cross-sectional study after the first wave","abstract":"BACKGROUND: Peru had the second-highest number of COVID-19 cases in Latin America. After the first wave, Peru registered more than 900,000 cases of COVID-19 and more than 36,000 confirmed deaths from the disease. Tumbes, a border area with poor sanitation and not enough water, had the fifth highest death rate. The cross-sectional analytic study aimed: a) to assess seroprevalence of COVID-19 after the first wave; b) to assess sociodemographic determinants and symptoms associated with a positive COVID-19 antibody lateral flow test. METHODOLOGY/PRINCIPAL FINDINGS: We performed this study between November 11th and November 30th, 2020, in an informal settlement in Tumbes. Individuals older than two years were invited to participate in a systematic random sample from one in every four households. Finger-prick blood samples were collected, and a census and symptom survey were applied. Within the chosen house, one adult over 18 years of age was chosen for a PCR-RT molecular test. Overall seroprevalence was 25.59%, adjusted seroprevalence was 24.82% (95%CI 22.49-27.25). Women had higher adjusted seroprevalence (28.03% vs 21.11%; 95% CI 24.83-31.41, p = 0.002). Symptoms as fever (PR 1.89: 95% CI 1.44-2.48, p<0.001), general discomfort (PR 1.67; 95% CI 1.23-2.26, p = 0.001), cough (PR 2.0; 95% CI 1.60-2.50, p<0.001), nasal congestion (PR 1.46; 95% CI 1.03-2.09, p = 0.036), respiratory distress (PR 1.64; 95% CI 1.04-2.56, p = 0.031), headache (PR 1.54; 95% CI 1.09-2.17, p = 0.014), anosmia (PR 1.78; 95% CI 1.01-3.14, p = 0.046) and ageusia (PR 2.31; 95% CI 1.48-3.61, p<0.001) were associated with a positive covid-19 antibody lateral flow test. CONCLUSIONS/SIGNIFICANCE: The COVID-19 transmission and distribution were highlighted by this cross-sectional study. The data will help the Ministry of Health improve its monitoring, surveillance, and monitoring of respiratory community sequelae in the future.","journal":"PLoS neglected tropical diseases","year":2023,"id":375046,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":4,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.949,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":1137283,"name":"Angie K. Toledo","orcid":"0000-0003-4418-8378","position":1,"is_corresponding":false},{"id":1137730,"name":"Jenny Chirinos","orcid":null,"position":2,"is_corresponding":false},{"id":1137731,"name":"Percy Mc Quen Vilchez Barreto","orcid":null,"position":3,"is_corresponding":false},{"id":139180,"name":"Sofia Cavalcanti","orcid":null,"position":4,"is_corresponding":false},{"id":785388,"name":"Ricardo Gamboa","orcid":null,"position":5,"is_corresponding":false},{"id":1137732,"name":"Jhon Ypanaque","orcid":null,"position":6,"is_corresponding":false},{"id":1137733,"name":"Mauro Meza","orcid":null,"position":7,"is_corresponding":false},{"id":1137734,"name":"Sheilla Noriega","orcid":null,"position":8,"is_corresponding":false},{"id":1137284,"name":"Víctor Gallego Herrera","orcid":"0000-0002-8552-4342","position":9,"is_corresponding":false},{"id":1137735,"name":"Edgar Bazan","orcid":null,"position":10,"is_corresponding":false},{"id":1137736,"name":"Alexandra Requena","orcid":null,"position":11,"is_corresponding":false},{"id":1137737,"name":"Henry Silva","orcid":null,"position":12,"is_corresponding":false},{"id":1137738,"name":"Harold Burgos","orcid":null,"position":13,"is_corresponding":false},{"id":1137285,"name":"Franco León-Jiménez","orcid":"0000-0002-9418-3236","position":14,"is_corresponding":false},{"id":1137739,"name":"Group of Neuroepidemiology and Science of Life of Peru","orcid":null,"position":15,"is_corresponding":false},{"id":784903,"name":"Luz M. Moyano","orcid":"0000-0002-5878-5782","position":0,"is_corresponding":true}],"reference_count":40,"raw_metadata":null,"created_at":"2026-07-19T01:16:19.336238Z","pmid":"37379355","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}