{"doi":"10.1371/journal.pgph.0003271","title":"Correlates of viral suppression among sexual minority men and transgender women living with HIV in Mpumalanga, South Africa","abstract":"Sexual minority men (SMM) and transgender women in South Africa engage in HIV care at lower rates than other persons living with HIV and may experience population-specific barriers to HIV treatment and viral suppression (VS). As part of a pilot trial of an SMM-tailored peer navigation (PN) intervention in Ehlanzeni district, South Africa, we assessed factors associated with ART use and VS among SMM at trial enrolment. A total of 103 HIV-positive SMM and transgender women enrolled in the pilot trial. Data on clinical visits and ART adherence were self-reported. VS status was verified through laboratory analysis (<1000 copies/ml). We assessed correlates of VS at baseline using Poisson generalized linear model (GLM) with a log link function, including demographic, psychosocial, clinical, and behavioral indicators. Among participants, 52.4% reported ART use and only 42.2% of all participants had evidence of VS. Of the 49.5% who reported optimal engagement in HIV care (consistent clinic visits with pills never missed for ≥ 4 consecutive days) in the past 3-months, 56.0% were virally suppressed. In multivariable analysis, SMM were significantly more likely to be virally suppressed when they were ≥ 25 years of age (Adjusted prevalence ratio [APR] = 2.0, CI 95%:1.0-3.8); in a relationship but not living with partner, as compared to married, living together, or single (APR = 1.7, CI 95%:1.0-2.7), and optimally engaged in care (APR = 2.1, 95% CI:1.3-3.3). Findings indicate a need for targeted treatment and care support programming, especially for SMM and transgender women who are young and married/living with their partners to improve treatment outcomes among this population.","journal":"PLOS Global Public Health","year":2024,"id":452267,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.961,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2024-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":827683,"name":"Alexander Marr","orcid":"0000-0002-1448-7353","position":1,"is_corresponding":false},{"id":404147,"name":"Kabelo Maleke","orcid":"0009-0009-1639-0721","position":2,"is_corresponding":false},{"id":404149,"name":"Albert Edgar Manyuchi","orcid":"0000-0001-7189-6201","position":3,"is_corresponding":false},{"id":420547,"name":"Ali Mirzazadeh","orcid":"0000-0002-0478-3220","position":4,"is_corresponding":false},{"id":405633,"name":"Oscar Radebe","orcid":null,"position":5,"is_corresponding":false},{"id":547084,"name":"Tim Lane","orcid":"0000-0002-2351-1204","position":6,"is_corresponding":false},{"id":412029,"name":"Adrian Puren","orcid":"0000-0001-7531-4010","position":7,"is_corresponding":false},{"id":363879,"name":"Wayne T. Steward","orcid":"0000-0002-9692-1968","position":8,"is_corresponding":false},{"id":1274061,"name":"Helen Struthers","orcid":"0000-0001-7468-3148","position":9,"is_corresponding":false},{"id":277333,"name":"Sheri A. Lippman","orcid":"0000-0003-3152-9372","position":10,"is_corresponding":false},{"id":790112,"name":"Akua O. Gyamerah","orcid":"0000-0003-3394-6532","position":0,"is_corresponding":true}],"reference_count":37,"raw_metadata":null,"created_at":"2026-07-19T02:02:50.407779Z","pmid":"39038019","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}