{"doi":"10.1371/journal.pcbi.0030119","title":"Protein–Protein Interaction Hotspots Carved into Sequences","abstract":null,"journal":"PLoS Computational Biology","year":2007,"id":31373,"datarank":10.404530803164706,"base_score":5.575949103146316,"endowment":5.575949103146316,"self_citation_contribution":0.8363923654719475,"citation_network_contribution":9.568138437692758,"self_endowment_contribution":0.8363923654719475,"citer_contribution":9.568138437692758,"corpus_percentile":null,"corpus_rank":null,"citation_count":263,"citer_count":200,"citers_with_citation_signal":200,"citers_with_endowment":200,"datacite_reuse_total":2,"is_dataset":false,"is_dataset_confidence":null,"is_oa":false,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":2331,"name":"Burkhard Rost","orcid":"0000-0003-0179-8424","position":1,"is_corresponding":false},{"id":124211,"name":"Yanay Ofran","orcid":null,"position":0,"is_corresponding":false}],"reference_count":0,"raw_metadata":{"has_enrichment":true,"base_score":5.575949103146316,"endowment":5.575949103146316,"datacite_reuse_total":2,"file_count":0,"downloads":0,"views":0,"has_version_chain":false,"is_dataset":false,"is_oa":false,"pmid":"17630824","pmcid":"PMC1914369","openalex_id":"https://openalex.org/W1985222378","authors":[],"funders":[{"funder_name":"NLM NIH HHS","grant_id":"2-R01-LM007329","title":null},{"funder_name":"NIGMS NIH HHS","grant_id":"R01-GM64633","title":null},{"funder_name":"NIGMS NIH HHS","grant_id":"R01 GM064633","title":null},{"funder_name":"NLM NIH HHS","grant_id":"R01 LM007329","title":null},{"funder_name":"National Institutes of Health","grant_id":"5R01GM064633-03","title":"Predicting putative protein-protein interface segments"},{"funder_name":"National Institutes of Health","grant_id":"7R01LM007329-08","title":"Improve predictions of structure and function by PredictProtein"}],"total_grants":6,"fwci":7.2658,"citation_percentile":0.9797797,"influential_citations":18,"citation_trend":[{"year":2012,"count":35},{"year":2013,"count":25},{"year":2014,"count":20},{"year":2015,"count":14},{"year":2016,"count":10},{"year":2017,"count":12},{"year":2018,"count":10},{"year":2019,"count":17},{"year":2020,"count":4},{"year":2021,"count":9},{"year":2022,"count":11},{"year":2023,"count":8},{"year":2024,"count":12},{"year":2025,"count":4},{"year":2026,"count":1}],"oa_status":"gold","license":"cc-by","oa_locations":[{"url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.0030119&type=printable","host_type":"journal"},{"url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.0030119&type=printable","host_type":"GOLD"},{"url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.0030119&type=printable","host_type":"publisher"},{"url":"https://dx.plos.org/10.1371/journal.pcbi.0030119","host_type":"publisher"},{"url":"https://doi.org/10.1371/journal.pcbi.0030119","host_type":"journal"},{"url":"https://pubmed.ncbi.nlm.nih.gov/17630824","host_type":"repository"},{"url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.279.9160","host_type":""},{"url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.0030119","host_type":"repository"},{"url":"https://doaj.org/article/4ef35e36c51d4148bf1b9a9a17538da7","host_type":"repository"},{"url":"http://europepmc.org/articles/PMC1914369","host_type":"repository"},{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1914369","host_type":"repository"},{"url":"https://europepmc.org/articles/PMC1914369","host_type":"Europe_PMC"},{"url":"https://europepmc.org/articles/PMC1914369?pdf=render","host_type":"Europe_PMC"},{"url":"http://dx.doi.org/10.1371/journal.pcbi.0030119","host_type":""},{"url":"https://dx.doi.org/10.1371/journal.pcbi.0030119","host_type":""}],"fields_of_study":["Protein Structure and Dynamics","Bioinformatics and Genomic Networks","Microbial Metabolic Engineering and Bioproduction","Biology","Computer Science","Medicine","0301 basic medicine","0303 health sciences","03 medical and health sciences","Amino Acid Sequence","Amino Acids","Binding Sites","Databases, Protein","Knowledge Bases","Models, Molecular","Multiprotein Complexes","Neural Networks, Computer","Predictive Value of Tests","Protein Binding","Protein Conformation","Protein Interaction Mapping","Proteins","Proteomics","Sequence Analysis, Protein","User-Computer Interface"],"mesh_terms":["Amino Acid Sequence","Amino Acids","Binding Sites","Models, Molecular","Predictive Value of Tests","Protein Binding","Protein Conformation","Proteins","User-Computer Interface","Neural Networks, Computer","Sequence Analysis, Protein","Protein Interaction Mapping","Databases, Protein","Proteomics","Multiprotein Complexes","Knowledge Bases"],"keywords":["In silico","Protein–protein interaction","Computational biology","Protein function","Protein structure prediction","Protein structure","Protein sequencing","Protein function prediction","Protein domain","Biology","Bioinformatics","Computer science","Peptide sequence","Genetics","Biochemistry","Models, Molecular","Proteomics","Binding Sites","QH301-705.5","Protein Conformation","Knowledge Bases","Proteins","User-Computer Interface","Predictive Value of Tests","Sequence Analysis, Protein","Multiprotein Complexes","Protein Interaction Mapping","Amino Acid Sequence","Neural Networks, Computer","Biology (General)","Amino Acids","Databases, Protein","Research Article","Protein Binding"],"sdg_mappings":[],"linked_datasets":[{"doi":"10.6084/m9.figshare.26668194.v1","title":"Additional file 1 of Intracellular delivery of Parkin-RING0-based fragments corrects Parkin-induced mitochondrial dysfunction through interaction with SLP-2","publisher":"figshare","resource_type":"JournalArticle"},{"doi":"10.6084/m9.figshare.26668194","title":"Additional file 1 of Intracellular delivery of Parkin-RING0-based fragments corrects Parkin-induced mitochondrial dysfunction through interaction with SLP-2","publisher":"figshare","resource_type":"JournalArticle"}],"clinical_trials":[],"software_tools":[],"database_accessions":[{"name":"pdb"}],"source":"live","citation_network_status":"fetched"},"created_at":"2026-06-09T07:01:19.805248Z","pmid":null,"pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}