{"doi":"10.1370/afm.2968","title":"Comparing Very Low-Carbohydrate vs DASH Diets for Overweight or Obese Adults With Hypertension and Prediabetes or Type 2 Diabetes: A Randomized Trial","abstract":"<h3>PURPOSE</h3> Adults with a triple multimorbidity (hypertension, prediabetes or type 2 diabetes, and overweight or obesity), are at increased risk of serious health complications, but experts disagree on which dietary patterns and support strategies should be recommended. <h3>METHODS</h3> We randomized 94 adults from southeast Michigan with this triple multimorbidity using a 2 × 2 diet-by-support factorial design, comparing a very low-carbohydrate (VLC) diet vs a Dietary Approaches to Stop Hypertension (DASH) diet, as well as comparing results with and without multicomponent extra support (mindful eating, positive emotion regulation, social support, and cooking). <h3>RESULTS</h3> Using intention-to-treat analyses, compared with the DASH diet, the VLC diet led to greater improvement in estimated mean systolic blood pressure (−9.77 mm Hg vs −5.18 mm Hg; <i>P</i> = .046), greater improvement in glycated hemoglobin (−0.35% vs −0.14%; <i>P</i> = .034), and greater improvement in weight (−19.14 lb vs −10.34 lb; <i>P</i> = .0003). The addition of extra support did not have a statistically significant effect on outcomes. <h3>CONCLUSIONS</h3> For adults with hypertension, prediabetes or type 2 diabetes, and overweight or obesity, the VLC diet resulted in greater improvements in systolic blood pressure, glycemic control, and weight over a 4-month period compared with the DASH diet. These findings suggest that larger trials with longer follow-up are warranted to determine whether the VLC diet might be more beneficial for disease management than the DASH diet for these high-risk adults.","journal":"The Annals of Family Medicine","year":2023,"id":323024,"datarank":1.2875004796942535,"base_score":3.6635616461296463,"endowment":3.6635616461296463,"self_citation_contribution":0.5495342469194471,"citation_network_contribution":0.7379662327748064,"self_endowment_contribution":0.5495342469194471,"citer_contribution":0.7379662327748064,"corpus_percentile":null,"corpus_rank":null,"citation_count":38,"citer_count":34,"citers_with_citation_signal":27,"citers_with_endowment":27,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9516,"is_data_producer":true,"deposit_databanks":{"ClinicalTrials.gov":["NCT03729479"]},"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2023-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":757505,"name":"Lenette M. Jones","orcid":"0000-0003-0994-5687","position":1,"is_corresponding":false},{"id":612770,"name":"Ananda Sen","orcid":"0000-0002-9632-6704","position":2,"is_corresponding":false},{"id":227313,"name":"Julia A. Wolfson","orcid":"0000-0001-9155-2609","position":3,"is_corresponding":false},{"id":1037685,"name":"Heidi L. Diez","orcid":null,"position":4,"is_corresponding":false},{"id":761113,"name":"Alison O’Brien","orcid":"0000-0002-8185-8118","position":5,"is_corresponding":false},{"id":227314,"name":"Cindy W. Leung","orcid":"0000-0001-6718-3487","position":6,"is_corresponding":false},{"id":413817,"name":"Hovig Bayandorian","orcid":"0000-0003-4596-0323","position":7,"is_corresponding":false},{"id":413814,"name":"Jennifer Daubenmier","orcid":"0000-0001-5678-4068","position":8,"is_corresponding":false},{"id":413816,"name":"Amanda L. Missel","orcid":"0000-0002-9879-0519","position":9,"is_corresponding":false},{"id":832831,"name":"Caroline R. Richardson","orcid":"0000-0002-1945-6046","position":10,"is_corresponding":false},{"id":413811,"name":"Laura R. Saslow","orcid":"0000-0003-3991-3205","position":0,"is_corresponding":true}],"reference_count":37,"raw_metadata":null,"created_at":"2026-07-19T01:07:47.432636Z","pmid":"37217318","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}