{"doi":"10.1370/afm.2878","title":"Ask-Advise-Connect: Differential Enrollment and Smoking Cessation Outcomes Between Primary Care Patients Who Received Quitline-Delivered Treatment in Spanish vs English","abstract":"<h3>PURPOSE</h3> This study examined differences in Quitline treatment enrollment, engagement, and smoking cessation outcomes among primary care patients preferring Spanish and English using the evidence-based tobacco treatment Ask-Advise-Connect. <h3>METHODS</h3> Ask-Advise-Connect was implemented April 2013 through February 2016 in a large safety-net health system to connect smokers with treatment via a link in the electronic health record. Rates of treatment enrollment, engagement, acceptance of nicotine replacement therapy, and smoking abstinence (self-reported and biochemically confirmed) were compared at 6 months among patients who received treatment in Spanish and English using <i>χ</i><sup>2</sup> tests. Logistic regression examined language and nicotine replacement therapy and their interaction as predictors of abstinence. <h3>RESULTS</h3> The smoking status of 218,915 patients was assessed and recorded in the electronic health record. Smoking prevalence was 8.4% among patients preferring Spanish and 27.0% among those preferring English. Spanish-preferring patients were less likely to enroll in treatment (10.7% vs 12.0%, <i>χ</i><sup>2</sup> = 12.06, <i>P</i> = .001) yet completed more counseling calls when enrolled (median = 2 vs 1, <i>P</i> &lt;.001). Patients who received treatment in Spanish (vs English) were twice as likely to be abstinent at 6 months (self-reported: 25.1% vs 14.5%, odds ratio [OR] = 1.98, 95% CI, 1.62-2.40; biochemically confirmed: 7.6% vs 3.7%, OR = 2.13, 95% CI, 1.52-2.97). Receipt of nicotine replacement therapy increased abstinence for all patients and language did not interact with nicotine replacement therapy to predict abstinence. <h3>CONCLUSIONS</h3> Automated point-of-care approaches such as Ask-Advise-Connect have great potential to reach Spanish-preferring smokers. Those who received tobacco treatment in Spanish (vs English) demonstrated better engagement and cessation outcomes.","journal":"The Annals of Family Medicine","year":2022,"id":291643,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":3,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9574,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2022-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":974899,"name":"Bárbara Piñeiro","orcid":"0000-0003-4225-3500","position":1,"is_corresponding":false},{"id":956051,"name":"Damon J. Vidrine","orcid":"0000-0002-8711-796X","position":2,"is_corresponding":false},{"id":959731,"name":"Summer G Frank-Pearce","orcid":"0000-0003-0779-4926","position":3,"is_corresponding":false},{"id":444101,"name":"David W. Wetter","orcid":"0000-0002-6366-0108","position":4,"is_corresponding":false},{"id":399198,"name":"Vani N. Simmons","orcid":"0000-0002-4381-5336","position":5,"is_corresponding":false},{"id":748225,"name":"Jennifer Irvin Vidrine","orcid":"0000-0002-9997-4459","position":6,"is_corresponding":false},{"id":919862,"name":"Bethany Shorey Fennell","orcid":"0000-0003-2188-6544","position":0,"is_corresponding":true}],"reference_count":34,"raw_metadata":null,"created_at":"2026-07-19T00:30:38.420009Z","pmid":"36443074","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}