{"doi":"10.1364/ol.547035","title":"Pupil wobble in point-scanning retinal optical coherence tomography systems","abstract":"Optical coherence tomography (OCT) systems utilize 2D scanning methods to acquire reflectance-based volumetric images of samples, such as the human retina, with micrometer-scale depth resolution. A common method for performing this scanning at high speeds is to use a pair of sequential, single-axis galvanometer scanners. An undesired effect of using separated scanners is the variation in the beam position at the pupil plane, a phenomenon known as beam wander or pupil wobble. This can lead to loss of signal and vignetting artifacts in the resulting images. To overcome these limitations, we propose a method to deterministically analyze the pupil wobble in a given retinal OCT system and to correct for the displacement using pupil tracking OCT with a 2D scanning mirror placed anti-conjugate to the pupil plane. We demonstrate that we can model the pattern of pupil wobble present in any OCT system both theoretically and empirically and then use a pupil tracking system to correct for the displacement of the beam to acquire OCT images without the imposed artifacts.","journal":"Optics Letters","year":2025,"id":550162,"datarank":0.0,"base_score":0.0,"endowment":0.0,"self_citation_contribution":0.0,"citation_network_contribution":0.0,"self_endowment_contribution":0.0,"citer_contribution":0.0,"corpus_percentile":null,"corpus_rank":null,"citation_count":2,"citer_count":0,"citers_with_citation_signal":0,"citers_with_endowment":0,"datacite_reuse_total":0,"is_dataset":false,"is_dataset_confidence":0.9615,"is_data_producer":false,"deposit_databanks":null,"is_oa":true,"file_count":0,"downloads":0,"has_version_chain":false,"published_date":"2025-01-01","fair_score":null,"fair_percentile":null,"algorithm_id":"datarank_citation_only_1hop_v6","ranking_scope":"data_only","authors":[{"id":662113,"name":"Pablo Ortiz","orcid":"0000-0002-3756-2440","position":1,"is_corresponding":false},{"id":304355,"name":"Mark Draelos","orcid":"0000-0002-5051-0880","position":2,"is_corresponding":false},{"id":522252,"name":"Ryan P. McNabb","orcid":"0000-0002-1686-4191","position":3,"is_corresponding":false},{"id":306352,"name":"Anthony N. Kuo","orcid":null,"position":4,"is_corresponding":false},{"id":304360,"name":"Joseph A. Izatt","orcid":"0000-0003-1993-2249","position":5,"is_corresponding":false},{"id":985402,"name":"Amit Narawane","orcid":"0000-0001-7881-8898","position":0,"is_corresponding":true}],"reference_count":11,"raw_metadata":null,"created_at":"2026-07-19T02:54:16.596730Z","pmid":"40085605","pmcid":null,"fwci":null,"citation_percentile":null,"influential_citations":0,"oa_status":null,"license":null,"views":0,"total_file_size_bytes":0,"version_count":0,"fair_f":null,"fair_a":null,"fair_i":null,"fair_r":null,"fair_zscore":null,"fair_rationale":null,"fair_model":null,"fair_agent_version":null,"fair_fulltext_source":null,"fair_has_llm":null,"fair_computed_at":null,"clinical_trials":[],"software_tools":[],"db_accessions":[],"linked_datasets":[],"topics":[]}